Clinical Trials Manager

Revolution Medicines, Inc.; California (MO); On-site; USD 120,000 - 180,000; Full time

Job summary

Revolution Medicines in Redwood City, CA is seeking a Clinical Trial Manager to oversee Phase I-III oncology clinical operations and CRO oversight, driving study execution across programs.

Responsibilities include vendor management, site visits, IP reconciliation, and leading clinical trial teams while ensuring GCP/ICH/FDA compliance and high-quality documentation. The role requires collaboration with cross-functional teams and travel up to 25%.

Qualifications

• BS/MS in life sciences or equivalent.
• 5+ years in clinical operations, preferably in oncology.
• Strong knowledge of FDA, ICH, and GCP guidelines.
• Vendor management experience in CRO/vendor oversight.

Responsibilities

• Manage clinical vendors and CROs ensuring alignment with study goals.
• Ensure trial compliance with GCP/ICH/FDA regulations and quality standards.
• Develop and review study documentation including protocols and ICFs.
• Conduct site visits, oversee investigational product reconciliation, and drug accountability.
• Lead clinical trial teams and cross-functional study governance.

Skills

Clinical trial management

Vendor management

CRO oversight

GCP/ICH/FDA knowledge

Education

BS/MS in life sciences

Job description

Role

Clinical Trial Manager overseeing Phase I-III oncology clinical operations at Revolution Medicines, focusing on CRO oversight and study execution.

Responsibilities

• manage clinical vendors, ensure trial compliance with GCP/ICH/FDA regulations, develop and review study documentation, conduct site visits, oversee investigational product reconciliation, and lead clinical trial teams.

Requirements

• BS/MS with 5+ years in clinical operations
• industry experience in early-phase oncology trials
• strong knowledge of FDA, ICH, GCP guidelines
• vendor management skills

Preferred

• experience with cooperative group studies, investigator-sponsored trials, and global/regional (APAC) clinical trial operations.

High Value

• oncology, Phase I-III, FDA/GCP compliance, vendor management, international trial oversight, ~25% travel.

Work Setup

onsite Redwood City, CA.