Clinical Research Coordinator II - Lead Complex Trials

Adams Clinical; Watertown (MA); On-site; USD 44,000 - 50,000; Full time

Benefits offered by this job

401(k) matching

Employee assistance program

Flexible spending account

Health insurance

Health savings account

Life insurance

Paid time off

Parental leave

Job summary

Adams Clinical in Watertown, MA is seeking a Clinical Research Coordinator II to oversee complex, high-enrolling trials within a dedicated portfolio. You will screen, enroll, conduct visits, manage start-up activities, and ensure data quality and regulatory readiness while collaborating closely with sponsors, monitors, and CROs.

The role requires at least 1 year of clinical research experience in industry-sponsored studies, strong protocol mastery, and excellent communication skills to support

Qualifications

• At least 1 year of prior clinical research experience. Industry-sponsored trials required.
• Ability to manage complex studies independently.
• Strong communication skills with sponsors and staff.

Responsibilities

• Manage a portfolio of complex and/or high-volume trials with guidance from a CRC III or the Site Manager, leading all operational and visit-related activities.
• Fully own study execution, including screening operations, enrollment progress, screening vs. target metrics, and SCF rates.
• Conduct all participant visits, clinical procedures, and eligibility assessments per protocol.
• Lead study start-up activities for assigned studies, including SIV preparation, regulatory readiness, supply planning, and supporting site completion of required staff training.
• Serve as the primary liaison with study sponsors, monitors, and CROs.
• Review source and eligibility criteria to ensure accurate screening and enrollment decisions.
• Train and supervise CRC I's or RA's supporting the portfolio; maintain quality and performance oversight.
• Lead data entry and query resolution efforts, ensuring high data quality and inspection readiness.
• Maintain investigational product (IP) accountability for assigned studies, including receipt, storage, dispensing, reconciliation, temperature monitoring, documentation, and proper disposal, ensuring compliance with protocol, regulatory requirements, and site SOPs.
• Identify operational risks and propose corrective actions to maintain study timelines and quality.
• Compile study metrics across assigned trials, including enrollment progress, screening performance, visit completion, and data quality.
• Prepare internal performance summaries for the site team and elevate issues or trends to senior staff.
• Present study metrics and operational updates to sponsors, monitors, or CRO leadership for assigned trials.
• Serve as a point of contact for resolving data queries and ensuring inspection readiness.

Skills

Clinical research experience

Independent study management

Communication skills

Job description

Adams Clinical in Watertown, MA is seeking a Clinical Research Coordinator II to oversee complex, high-enrolling trials within a dedicated portfolio. You will screen, enroll, conduct visits, manage start-up activities, and ensure data quality and regulatory readiness while collaborating closely with sponsors, monitors, and CROs.

The role requires at least 1 year of clinical research experience in industry-sponsored studies, strong protocol mastery, and excellent communication skills to support