Clinical Laboratory Scientist

CLS Connect; Milpitas (CA); On-site; USD 83,000 - 92,000; Full time

Job summary

CLS Connect in Milpitas, CA is seeking a Clinical Laboratory Scientist to join our onsite team. You will perform and oversee high‑complexity molecular testing, including DNA extraction, sample preparation, and NGS workflows.

You must hold a California CLS license (Generalist or CGMBS), have a strong background in molecular diagnostics, and be prepared to support laboratory build‑out, process improvements, and regulatory compliance. Mon-Fri, no sponsorship.

Qualifications

• Active California CLS license as Generalist or CGMBS.
• Minimum 3 years in molecular diagnostics or high-complexity CLIA labs.
• Experience establishing or scaling NGS-based clinical testing.

Responsibilities

• Perform and oversee high-complexity molecular testing, including DNA extraction, sample preparation, and NGS workflows.
• Review and verify test results according to laboratory SOPs and regulatory requirements.
• Ensure CLIA, CAP, and California Department of Public Health regulations compliance.
• Support scaling and optimization of high-throughput laboratory workflows.

Skills

Molecular diagnostics

NGS workflows

DNA extraction

Regulatory compliance

Laboratory operations

Education

B.S. in Biochemistry, Molecular Biology, or related field

Tools

NGS platforms

DNA extraction equipment

Job description

*** U.S. Residents Only -- No Sponsorship ***

Clinical Laboratory Scientist

California CLS license REQUIRED – Generalist or CGMBS

Full-Time, Direct-Hire, Onsite in Milpitas

Monday–Friday 8am–4:30pm

$60–$67/hour (based on exp)

Required Qualifications:

• Active California CLS license as a Generalist or Clinical Genetic Molecular Biologist Scientist (CGMBS).
• B.S. in Biochemistry, Molecular Biology, or related field.
• 3+ years of experience in molecular diagnostics or high-complexity CLIA laboratories.
• Demonstrated experience establishing or scaling NGS-based clinical testing.
• Strong hands‑on experience with DNA extraction, sample preparation, and high‑throughput NGS platforms.
• Deep understanding of CLIA/CAP regulatory standards.
• Proven ability to implement process improvements and optimize laboratory operations.

Key Responsibilities:

Clinical Operations & High-Complexity Testing

• Perform and oversee high-complexity molecular testing, including DNA extraction, sample preparation, and NGS workflows.
• Review and verify test results according to laboratory SOPs and regulatory requirements.
• Ensure compliance with CLIA, CAP, and California Department of Public Health regulations.

Laboratory Build & Optimization

• Support scaling and optimization of high-throughput NGS laboratory workflows.
• Contribute to laboratory build‑out, workflow standardization, and documentation systems.
• Lead assay improvements and platform transitions when required.
• Implement process improvements to increase throughput, data quality, and operational efficiency.

Quality & Regulatory Compliance

• Maintain inspection readiness and support CLIA/CAP audits
• Oversee QC monitoring, deviation tracking, and corrective actions
• Participate in validation and verification of new assays and instrumentation
• Ensure rigorous data integrity and standardized documentation practices