Clinical Bioinformatics Analyst I

Foundation Medicine; Boston (MA); On-site; USD 66,000 - 83,000; Full time

Job summary

Foundation Medicine is seeking an Analyst I, Clinical Bioinformatics to analyze and deliver NGS data in a regulated clinical diagnostic laboratory, collaborating with clinicians, pharma partners, and academic collaborators.

This role involves developing genomic profiles, reviewing variant calls with IGV, and delivering results per SOPs within defined turnaround times. A CLIA lab background and strong collaboration skills are essential.

Qualifications

• Bachelor’s degree in a bioinformatics or life science field.
• Experience with bioinformatics tools and databases.
• Ability to work in a CLIA-certified clinical diagnostics lab.
• Experience with Next-Generation Sequencing.
• Willingness to work weekends or off-hours shifts.
• Strong written and oral communication and collaboration skills.

Responsibilities

• Develop annotated genomic profiles of somatic aberrations from NGS data.
• Review genomic variant calls using IGV and other tools.
• Provide test results per SOPs within defined turnaround times.
• Collaborate with technical teams to specify requirements for tools and workflows.
• Comply with attendance policies and company norms.
• Other duties as assigned.

Skills

Bioinformatics tools

Python/Perl scripting

UNIX environment

Next-Generation Sequencing

Clinical diagnostics

Education

Bachelor’s Degree

Master’s Degree in Bioinformatics/Biology/life science

Tools

IGV

NCBI

UCSC Genome Browser

Job description

About the Job:

The Analyst I, Clinical Bioinformatics is responsible for analysis and delivery of next generation sequence data in a high-complexity clinical diagnostic laboratory to clinicians, pharmaceutical partners, and academic collaborators. In addition, the position is responsible for collecting and presenting quality metrics and reviewing variant reports.

This is a regulated position and additional information may be available from QA on the qualifications for this role pertaining to regulatory guidelines.

Key Responsibilities:

• Develop annotated genomic profiles of somatic aberrations based on massively-parallel sequencing (Next Generation Sequencing or NGS) data in cancer-patient samples study.
• Review genomic variant calls using proprietary and publicly available tools, including but not limited to the Integrative Genomics Viewer (IGV), in close collaboration with the scientific team.
• Provide test results according to Standard Operating Procedures (SOPs) with the best possible quality within defined turn‑around times.
• Collaborate with technical teams in specifying requirements for tools to enhance workflow efficiency and robustness.
• Other duties as assigned.
• Comply with FMI's attendance policies

Qualifications:

Basic Qualifications:

• Bachelor’s Degree
• Prior experience working with bioinformatics tools and databases

Preferred Qualifications:

• Master’s Degree in Bioinformatics, Biology, or a life science
• Substantive genomics research experience in rigorous academic setting
• Experience with bioinformatics tools and databases, including the National Center for Biotechnology Information (NCBI), University of California Santa Cruz (UCSC) Genome Browser, and Integrative Genomics Viewer (IGV)
• Scripting ability in Python or Perl
• Facility with UNIX environment
• Experience with Next-Generation Sequencing
• Experience working within a CLIA-certified clinical diagnostics laboratory
• Ability to work in a lab environment in the presence of chemicals and regents
• Ability to work weekend or off-hours shift work
• Strong interpersonal skills that include excellent skills in written and oral communication, collaboration, and problem solving
• Demonstrated history of successfully managing multiple concurrent initiatives and maintaining one’s own workflow
• Demonstrated ability to meet project deadlines
• Ability to work well under pressure while maintaining a professional demeanor
• Understanding of HIPAA and the importance of patient data privacy
• Commitment to reflect FMI’s values: Integrity, Courage, and Passion

The expected salary range for this position based on the primary location of Boston, MA is $66,200 – $82,700 per year. The salary range is commensurate with Foundation Medicines compensation practice and considers factors including, but not limited to, education, training, experience, external market conditions, criticality of role, and internal equity. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for Foundation Medicine's benefits.

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