Chief of Staff

Esperion Therapeutics Inc; Ann Arbor (MI); Hybrid; USD 270,000 - 300,000; Full time

Benefits offered by this job

Bonus program

Long-term incentives

401(k) matching

Health insurance

Paid time off

Job summary

Esperion Therapeutics Inc. is seeking a Chief of Staff to partner with the CEO, align strategic priorities, and drive high-impact initiatives in a fully remote role based in the US. The position focuses on enterprise-wide execution, governance, and cross-functional program leadership.

The ideal candidate brings 8+ years in leadership/strategy roles, strong communication, and a proactive approach to complex program management within biotech, with competitive compensation and long-term incentives.

Qualifications

• Bachelor’s degree in Business, Marketing, or healthcare-related field; 8+ years in business management/leadership/strategy/operations.
• Experience supporting executive leadership teams in fast-paced environments.
• Experience in planning and leading strategic initiatives; leading cross-functional programs.

Responsibilities

• Strategic Alignment & Executive Operating Rhythm: manage annual planning, reviews, and KPI tracking.
• Cross-Functional Execution & Project Ownership: drive CEO-led initiatives across multiple functions.
• Communication: facilitate information flow between CEO, leadership, and employees; mediate disputes.
• CEO Strategic Support: prioritize enterprise-wide initiatives and ensure timely follow-through.
• Board and Investor Preparation: assist with materials for board and investor updates.
• Decision Support and Business Insights: analyze performance, trends, and risks to inform leadership.
• Biotech Business Operations: support product strategy, lifecycle planning, and organizational scaling.

Skills

Strategic thinking

Executive communications

Cross-functional leadership

Project management

Budget management

Data analysis

Education

Bachelor’s degree in Business/Marketing/healthcare

MBA preferred

Tools

Microsoft Office Suite

Job description

If you are unable to complete this application due to a disability, contact this employer to ask for an accommodation or an alternative application process.

Chief of Staff

Full Time Professional Remote, Ann Arbor, MI, US

2 days ago Requisition ID: 1803

Salary Range: $270,000.00 To $300,000.00 Annually

Company Overview

Our Mission: At Esperion, we are working tirelessly to deliver innovative medicines that help patients reach their goals today, tomorrow, and into the future.

Esperion is a fully remote based company with a corporate headquarters located in Ann Arbor, MI. Esperion is a privately held, private equity-backed commercial-stage company. The Company offers a competitive salary including a performance-based bonus program and a long-term incentive plan, a comprehensive benefits package including a 401(k) matching plan and health insurance, and paid time off and holidays.

Position Title: Chief of Staff

A Chief of Staff serves as a strategic execution partner, a force multiplier, and a central communications bridge for the CEO, tracking enterprise priorities and managing special projects that support the organization’s growth and value creation objectives.

Preferred Location: Remote – US

Essential Duties and Responsibilities*

• Strategic Alignment & Executive Operating Rhythm: Manages the rhythm of business, including annual strategic planning and business review processes, board meeting preparation, and tracking organizational goals, key performance indicators, and value creation objectives.
• Cross-Functional Execution & Project Ownership: Drive coordination across Commercial, Medical Affairs, Regulatory, Market Access, Finance, Legal, and other functions to advance high-impact business objectives and remove barriers to execution. Leads cross-functional, high-priority special projects that do not fall under a single department.
• Communication: Facilitates the flow of information between the CEO, leadership team, and employees, while helping mediate disputes. Supports leadership engagement and culture-building activities.
• CEO Strategic Support: Partner directly with the CEO to prioritize enterprise-wide initiatives, prepare for key decisions, and ensure timely follow-through on strategic commitments.
• Board and Investor Preparation: Support the preparation of Board of Directors materials, investor updates, executive presentations, and briefing documents that clearly communicate business performance, priorities, risks, and opportunities.
• Decision Support and Business Insights: Analyze business updates, performance metrics, market trends, and functional reports to synthesize insights, identify risks, and recommend actions for CEO and executive leadership consideration.
• Biotech Business Operations: Support initiatives related to product strategy, commercialization readiness, lifecycle planning, corporate development, alliance management, and organizational scaling in a highly regulated biotech environment.

*Additional duties and responsibilities as assigned

Qualifications (Education & Experience)

• Bachelor’s degree in Business, Marketing, or health-care related field, eight or more years of experience in a business management, leadership, strategy, consulting or operations role, MBA preferred.
• Experience supporting executive leadership teams in a fast-paced environment.
• Experience in planning and leading strategic initiatives
• Demonstrated success leading complex cross-functional initiatives.
• Excellent written and verbal communication skills
• Versatile abilities and extreme dedication to efficient productivity
• Experience in data analysis and budget management
• Consulting experience, with a focus on operations management
• Proven success in a project coordination role
• Nimble business mind, focused on developing creative solutions
• Strong project-reporting skills, with focus on interdepartmental communications
• Experience preparing materials for executive committees or boards of directors preferred.
• Advanced proficiency with Microsoft Office Suite, including PowerPoint and Excel.
• High level of professionalism, judgment, and discretion.