Chief of Staff

Socket.dev; Michigan; Hybrid; USD 120,000 - 180,000; Full time

Job summary

Esperion is seeking a Chief of Staff to serve as a strategic execution partner for the CEO, driving enterprise priorities and coordinating high-impact initiatives.

The role spans cross-functional project ownership, board/investor prep, and executive communications, with a focus on delivering timely follow-through and business insights in a fully remote US setting.

Qualifications

• Bachelor’s degree in Business, Marketing, or health-care related field; MBA preferred.
• Experience supporting executive leadership teams in fast-paced environments.
• Experience in planning and leading strategic initiatives and cross-functional projects.
• Excellent written and verbal communication skills are essential.
• Proficiency with Microsoft Office, especially PowerPoint and Excel.

Responsibilities

• Manage the rhythm of business, including annual strategic planning and board prep.
• Coordinate cross-functional projects across Commercial, Medical Affairs, Regulatory, Market Access, Finance, Legal, and other functions.
• Facilitate CEO communications and leadership engagement; support culture initiatives.
• Prepare materials for Board of Directors and investor updates; give executive presentations.
• Analyze business updates, performance metrics, and market trends to identify risks and opportunities.
• Support biotech operations relating to strategy, lifecycle planning, and alliance management.

Skills

Strategic thinking

Cross-functional collaboration

Communication skills

Budget management

Data analysis

Project coordination

Education

Bachelor’s degree in Business, Marketing, or health-care related field

MBA preferred

Tools

PowerPoint

Excel

MS Office Suite

Job description

Company Overview

Esperion is a fully remote based company with a corporate headquarters located in Ann Arbor, MI. Esperion is a privately held, private equity-backed commercial-stage company. The Company offers a competitive salary including a performance-based bonus program and a long-term incentive plan, a comprehensive benefits package including a 401(k) matching plan and health insurance, and paid time off and holidays.

Our Mission:

At Esperion, we are working tirelessly to deliver innovative medicines that help patients reach their goals today, tomorrow, and into the future.

Position Title: Chief of Staff

A Chief of Staff serves as a strategic execution partner, a force multiplier, and a central communications bridge for the CEO, tracking enterprise priorities and managing special projects that support the organization’s growth and value creation objectives.

Preferred Location: Remote – US

Essential Duties and Responsibilities*

• Strategic Alignment & Executive Operating Rhythm: Manages the rhythm of business, including annual strategic planning and business review processes, board meeting preparation, and tracking organizational goals, key performance indicators, and value creation objectives.
• Cross-Functional Execution & Project Ownership: Drive coordination across Commercial, Medical Affairs, Regulatory, Market Access, Finance, Legal, and other functions to advance high-impact business objectives and remove barriers to execution. Leads cross-functional, high-priority special projects that do not fall under a single department.
• Communication: Facilitates the flow of information between the CEO, leadership team, and employees, while helping mediate disputes. Supports leadership engagement and culture-building activities.
• CEO Strategic Support: Partner directly with the CEO to prioritize enterprise-wide initiatives, prepare for key decisions, and ensure timely follow-through on strategic commitments.
• Board and Investor Preparation: Support the preparation of Board of Directors materials, investor updates, executive presentations, and briefing documents that clearly communicate business performance, priorities, risks, and opportunities.
• Decision Support and Business Insights: Analyze business updates, performance metrics, market trends, and functional reports to synthesize insights, identify risks, and recommend actions for CEO and executive leadership consideration.
• Biotech Business Operations: Support initiatives related to product strategy, commercialization readiness, lifecycle planning, corporate development, alliance management, and organizational scaling in a highly regulated biotech environment.

*Additional duties and responsibilities as assigned

Qualifications (Education & Experience)

• Bachelor’s degree in Business, Marketing, or health-care related field, eight or more years of experience in a business management, leadership, strategy, consulting or operations role, MBA preferred.
• Experience supporting executive leadership teams in a fast-paced environment.
• Experience in planning and leading strategic initiatives
• Demonstrated success leading complex cross-functional initiatives.
• Excellent written and verbal communication skills
• Versatile abilities and extreme dedication to efficient productivity
• Experience in data analysis and budget management
• Consulting experience, with a focus on operations management
• Proven success in a project coordination role
• Nimble business mind, focused on developing creative solutions
• Strong project-reporting skills, with focus on interdepartmental communications
• Experience preparing materials for executive committees or boards of directors preferred.
• Advanced proficiency with Microsoft Office Suite, including PowerPoint and Excel.
• High level of professionalism, judgment, and discretion.