Chief Medical Officer

Hlx Life Sciences; Boston (MA); On-site; USD 250,000 - 350,000; Full time

Job summary

A clinical-stage biotechnology company is seeking a hands-on Chief Medical Officer in Boston. This strategic role involves leading clinical development for their Phase II programmes with a focus on nephrology. The ideal candidate will work closely with the CEO and engage with KOLs and investors. Responsibilities include overseeing trial management, regulatory interactions, and shaping company strategy. This is a unique opportunity to contribute significantly to a company focused on innovative therapies for rare renal diseases.

Qualifications

• MD or MD/PhD; strong preference for nephrology expertise.
• Proven track record in leading clinical development programmes.
• Experience with investors and key opinion leaders is essential.

Responsibilities

• Lead clinical development strategy for Phase II programme.
• Oversee trial design, execution, and data interpretation.
• Act as a partner to the CEO on strategy and growth.

Skills

Clinical development

Investor engagement

Regulatory interactions

Communication skills

Nephrology expertise

Education

MD or MD/PhD

Job description

Hlx is partnering with a clinical-stage biotechnology company developing innovative therapies for rare renal diseases. With a lead programme in Phase II, the company is entering a critical stage of development and value creation.

We are seeking a hands‑on Chief Medical Officer to work closely with the CEO as a true strategic partner. This role combines leadership and execution, with a strong emphasis on external engagement across investors, Key Opinion Leaders, and partners. The successful candidate will play a central role in shaping both the clinical strategy and the broader company narrative.

Responsibilities

• Lead the clinical development strategy and execution for the company’s Phase II programme and pipeline
• Provide hands‑on oversight of trial design, execution, and data interpretation in a lean operating model
• Act as a key partner to the CEO on company strategy, prioritisation, and growth initiatives
• Play a central role in investor engagement, including fundraising, diligence, and presenting to investors and the Board
• Build and maintain strong relationships with global KOLs, investigators, and patient advocacy groups
• Represent the company at scientific congresses and industry events
• Lead regulatory interactions (FDA, EMA) and overall development pathway
• Integrate translational insights, including biomarkers and patient stratification strategies
• Support the build‑out of the clinical and medical function as the company scales

Qualifications

• MD or MD/PhD; nephrology expertise strongly preferred – ideally nephrologist or cardio/metabolic focused
• Proven track record leading clinical development programmes through Phase II
• Demonstrated experience working closely with investors and KOLs in an externally facing capacity
• Prior experience in a small or mid‑sized biotech environment preferred
• Strong strategic and operational capabilities; able to operate in a hands‑on, resource‑conscious setting
• Excellent communication skills with the ability to translate complex science for diverse audiences
• Credible external presence with regulators, investigators, and the investment community

Next Steps

For a confidential discussion or to express interest, please get in touch directly. We are actively engaging with a select group of candidates and welcome early conversations.