Cardiovascular Senior Scientist at Metric Bio Boston, MA

Downtown Boulder Partnership; Boston (MA); On-site; USD 90,000 - 120,000; Full time

Job summary

Metric Bio is seeking a Cardiovascular Senior Scientist in Boston, MA. This role focuses on pioneering drug discovery, requiring in-depth expertise in cardiovascular biology and assay optimization. The successful candidate will lead scientific areas, contribute to innovative research, and mentor team members.

Candidates should possess a Ph.D., strong publication record, and at least 2 years of postdoctoral experience. This exciting opportunity fosters collaboration within a fast-paced environment.

Qualifications

• Ph.D. in cardiovascular biology, cell biology, molecular biology, biochemistry, or a related field.
• Strong background in cardiovascular physiology and its applications.
• At least 2+ years of relevant postdoctoral experience.

Responsibilities

• Design, develop, and execute pharmacological assays.
• Independently design and validate cell-based assays.
• Lead scientific subject areas within the team.

Skills

Cardiovascular biology expertise

Cell and molecular biology

Assay optimization for drug discovery

Collaboration

Mentoring

Education

Ph.D. in related field

Tools

CRISPR

RT-PCR

Viral vectors

Job description

Cardiovascular Senior Scientist – Metric Bio, Boston, MA

Metric Bio has partnered with a client focused on cardiovascular research and drug discovery.

We are seeking a forward-thinking, curious, and innovative Cardiovascular Scientist or Senior Scientist to join a pioneering team at the forefront of condensate‑focused drug discovery. This role requires deep expertise in cardiovascular biology, cell and molecular biology, and assay optimization for cardiovascular drug discovery. The successful candidate will collaborate with cross‑functional teams to advance discovery programs that have the potential to transform patient outcomes.

Responsibilities:

• Design, develop, and execute pharmacological assays to support innovative drug discovery programs.
• Independently design, optimize, and validate cell‑based assays for cardiovascular research.
• Lead scientific subject areas within the team, serving as a key contributor and thought leader.
• Collaborate with cross‑functional colleagues to ensure biological relevance of assays and alignment with program goals.
• Mentor and inspire team members, fostering a culture of learning and scientific excellence.
• Contribute to scientific visibility through project deliverables, internal presentations, and external conference participation or publications.
• Participate in additional initiatives and projects in a dynamic, fast‑paced environment.

Qualifications:

• Ph.D. in cardiovascular biology, cell biology, molecular biology, biochemistry, or a related field.
• Strong background in cardiovascular physiology and its applications.
• At least 2+ years of relevant postdoctoral experience with a proven track record of scientific achievement.
• Strong publication record demonstrating impactful contributions to the field.
• Expertise in designing and implementing cell‑based assays for drug discovery.
• Hands‑on experience with pharmacological assays for cardiomyocytes, including calcium flux, contractility, and/or electrophysiology techniques.
• Proficiency in working with 2D and 3D cardiac model systems.
• Proficiency in molecular biology techniques such as RT‑PCR, CRISPR, siRNA, viral vectors, and transcription analysis.
• Exceptional organizational skills with the ability to balance multiple objectives and deliver on timelines.
• Ability to thrive in a multidisciplinary, fast‑paced environment while remaining solution‑oriented and organized.
• Fluent communication skills in English for effective collaboration within a multicultural team.

Additional Preferred Experience:

• At least 2+ years of relevant industry experience in biotechnology, pharmaceuticals, or life sciences.
• Expertise in assay analysis, including evaluating compound potency and dynamic response ranges.
• Experience developing in vivo pharmacological assays using animal models.
• Proficiency in optimizing and validating robotic‑based assays for high‑throughput screening, particularly with high‑content imaging technologies.
• Strong background in in‑vitro assay development, execution, and high‑content screening, including cellular imaging techniques.

This role offers an exciting opportunity for an innovative and collaborative scientist eager to contribute to groundbreaking discoveries. If you are passionate about cardiovascular research and drug discovery, we encourage you to apply!