Cardiac iPSC Scientist: Model Development & Assays

insitro; South San Francisco (CA); On-site; USD 107,000 - 114,000; Full time

Benefits offered by this job

401(k) plan with employer matching

Medical, dental, vision coverage

Open vacation policy

Paid parental leave

Job summary

insitro is seeking an Associate Scientist III to advance iPSC-derived cardiomyocyte models for cardiovascular disease. You will work on differentiation workflows, characterize cellular models, and develop scalable assays connecting phenotypes to disease mechanisms, reporting to Senior Scientist, Cardiometabolic Disease - Translational Genetics.

The role is based in South San Francisco, onsite 5 days per week.

Qualifications

• Bachelor’s or Master’s degree with 2+ years in biotech/biopharma
• Hands-on iPSC culture and cardiomyocyte differentiation in 2D
• Genetic disease modeling using patient-derived or edited lines
• Experience with functional assays for cardiomyocytes (contractility, electrophysiology, Ca2+ handling)
• Molecular assays (PCR, RT-qPCR, Western blot, immunofluorescence)
• Strong scientific communication and ability to document rigorously

Responsibilities

• Support development of iPSC-CM models and differentiation workflows
• Develop and optimize functional assays for cardiovascular disease in high-throughput formats
• Document procedures, present results, and maintain rigorous lab notebooks
• Contribute to target identification by linking cellular phenotypes to human genetic evidence

Skills

iPSC-CM Platform & Model Development

Genetic Disease Modeling

Cardiovascular Biology

Functional Assays

Molecular Assays

Scientific Communication

Cross-functional Collaboration

Independent & Adaptive

Education

Bachelor’s or Master’s in biology/biochemistry or related

Job description

insitro is seeking an Associate Scientist III to advance iPSC-derived cardiomyocyte models for cardiovascular disease. You will work on differentiation workflows, characterize cellular models, and develop scalable assays connecting phenotypes to disease mechanisms, reporting to Senior Scientist, Cardiometabolic Disease - Translational Genetics.

The role is based in South San Francisco, onsite 5 days per week.