Biologist: Single-Cell Sequencing Scientist

JobDiva, Inc.; Boston (MA); On-site; USD 66,000 - 79,000; Full time

Benefits offered by this job

Health insurance

Health savings account

Dental insurance

Vision insurance

Flexible spending accounts

Life insurance

Retirement plan

Job summary

JobDiva, Inc. is seeking a Biologist: Single-Cell Sequencing Scientist in Boston to support RNA-seq and single-cell sequencing efforts within a Cardiometabolic Research team.

The role centers on library preparation workflows and collaboration across therapeutic areas to advance drug discovery. The position emphasizes hands-on molecular biology, preparation of scRNA-seq/snRNA-seq libraries, and leveraging multiple platforms (e.g., 10x Genomics Chromium) while maintaining meticulous documentation

Qualifications

• Bachelor’s and/or Master’s degree in biological sciences, biochemical sciences, or a related field.
• 2 years of laboratory research experience.
• Strong hands-on molecular biology experience, including nucleic acid extraction and purification, quantification, NGS library preparation, quality control, and qPCR.
• Strong knowledge of next-generation sequencing technologies and applications, preferably including Illumina platforms.
• Direct experience with bulk RNA-seq and amplicon sequencing.
• Direct experience preparing single-cell RNA-seq and single-nucleus RNA-seq libraries.
• Experience with multiple scRNA-seq/snRNA-seq platforms, such as 10x Genomics Chromium, Illumina PIP-seq, ScaleBio, or Parse Biosciences.
• Strong organizational, time-management, documentation, and communication skills.
• Experience documenting laboratory activities in electronic laboratory notebook systems.

Responsibilities

• Perform RNA-seq, scRNA-seq, snRNA-seq, and other next-generation sequencing library preparation workflows.
• Conduct molecular and cell biology experiments supporting drug discovery programs.
• Design and execute experiments to identify and validate potential drug targets.
• Support assay development, optimization, and validation.
• Perform nucleic acid extraction, purification, quantification, library preparation, and quality-control testing.
• Troubleshoot experimental workflows and analyze complex laboratory data.
• Support sequencing data generation and quality-control activities.
• Collaborate with cross-functional research teams across multiple therapeutic areas.
• Maintain accurate and detailed experimental documentation.
• Present experimental results, findings, and conclusions through written reports and verbal presentations.

Skills

Molecular biology

Next-gen sequencing

RNA-seq

scRNA-seq

snRNA-seq

Illumina platforms

Nucleic acid extraction

qPCR

Lab notebook

Cross-functional collaboration

Education

Bachelor’s or Master’s in biological sciences

Tools

10x Genomics Chromium

Illumina sequencing

ELN systems

Job description

Biologist: Single-Cell Sequencing Scientist

Location: Boston, MA 02210– 100% Onsite
Pay Rate: $48.00–$57.28/hour
Duration: 6-Month Contract with Potential Extension
Schedule: Monday–Friday, 8:00 AM–5:00 PM

Overview

The Biologist will join the Cardiometabolic Research team and support drug discovery and early-stage clinical research focused on diabetes, obesity, cardiovascular disease, and related metabolic disorders.

This position will primarily support next-generation sequencing initiatives, including RNA-seq, single-cell RNA-seq, single-nucleus RNA-seq, and other sequencing library preparation workflows. The role will collaborate across multiple research groups and therapeutic areas to support molecular biology, assay development, target identification, and data generation.

Required Qualifications

• Bachelor’s and/or Master’s degree in biological sciences, biochemical sciences, or a related field.
• 2 years of laboratory research experience.
• Strong hands-on molecular biology experience, including nucleic acid extraction and purification, quantification, NGS library preparation, quality control, and qPCR.
• Strong knowledge of next-generation sequencing technologies and applications, preferably including Illumina platforms.
• Direct experience with bulk RNA-seq and amplicon sequencing.
• Direct experience preparing single-cell RNA-seq and single-nucleus RNA-seq libraries.
• Experience with multiple scRNA-seq/snRNA-seq platforms, such as 10x Genomics Chromium, Illumina PIP-seq, ScaleBio, or Parse Biosciences.
• Strong organizational, time-management, documentation, and communication skills.
• Experience documenting laboratory activities in electronic laboratory notebook systems.

Preferred Qualifications

• Experience with CRISPR-based gene editing and high-throughput screening.
• Experience with laboratory automation systems, such as Mantis, Integra, liquid handlers, SPT Labtech Firefly, or Tecan.

Responsibilities

• Perform RNA-seq, scRNA-seq, snRNA-seq, and other next-generation sequencing library preparation workflows.
• Conduct molecular and cell biology experiments supporting drug discovery programs.
• Design and execute experiments to identify and validate potential drug targets.
• Support assay development, optimization, and validation.
• Perform nucleic acid extraction, purification, quantification, library preparation, and quality-control testing.
• Troubleshoot experimental workflows and analyze complex laboratory data.
• Support sequencing data generation and quality-control activities.
• Collaborate with cross-functional research teams across multiple therapeutic areas.
• Maintain accurate and detailed experimental documentation.
• Present experimental results, findings, and conclusions through written reports and verbal presentations.

Benefits

Employee contribution may apply.

• Health insurance
• Health savings account
• Dental insurance
• Vision insurance
• Flexible spending accounts
• Life insurance
• Retirement plan

All qualified applicants will receive consideration for employment without regard to age, race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or protected veteran status. Rate of pay within the stated range will depend on the qualifications of the applicant.
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