Scientist / Senior Scientist, NGS R&D

Complete Genomics Incorporated; San Jose (CA); On-site; USD 90,000 - 110,000; Full time

Benefits offered by this job

Wellness: Gym membership reimbursement

Employee Discounts

Comprehensive benefits package

Job summary

Complete Genomics Incorporated in San Jose, CA, seeks a Scientist / Senior Scientist, NGS R&D, to lead the design, development, and optimization of sequencing workflows, library preparation chemistries, and targeted screening panels.

Working across molecular biology, chemistry, and data science, you will collaborate across disciplines to translate concepts into real-world sequencing applications, contribute to SOPs and IP filings, and drive rigorous, data-driven experimentation on-site.

Qualifications

• Ph.D. required in a life sciences field.
• 0–5+ years hands-on NGS experience preferred.
• Experience designing and optimizing sequencing workflows and assays.
• Strong publication or IP development track record helpful.

Responsibilities

• Design and optimize sequencing workflows and library preparation chemistries.
• Evaluate and integrate emerging sequencing platforms and microfluidic technologies.
• Plan and execute complex laboratory experiments with a data-driven approach.
• Collaborate with engineering, bioinformatics, and software teams on R&D projects.
• Document SOPs and contribute to IP filings and regulatory submissions.

Skills

NGS Expertise

Sequencing Workflow Development

Platform & Microfluidics Experience

Technical Knowledge

Scientific Research & Development

Cross-Functional R&D Experience

Education

Ph.D. in Molecular Biology, Genetics, Biochemistry, Bioengineering, Chemical Engineering, or related life sciences

Job description

Are you ready to develop sequencing technologies that could shape the next generation of genomics and multi-omics?

Do you want to advance CoolMPS, our innovative sequencing chemistry designed to advance the accuracy and performance of next-generation sequencing, and help turn new scientific ideas into real-world sequencing applications?

Do you thrive in an environment with diversity, communication, collaboration, and teamwork as the core values?

As a Scientist / Senior Scientist, NGS R&D, you will drive the design, development, and optimization of novel sequencing workflows, library preparation chemistries, and targeted screening panels. Working at the intersection of molecular biology, advanced chemistry, and data science, you will collaborate across disciplines to advance new sequencing technologies from concept toward application.

WHAT YOU WILL BE DOING

• Develop NGS Assays: Design and optimize novel sample arraying and sequencing workflow strategies for different applications.
• Advance Sequencing Technology: Evaluate, benchmark, and integrate emerging sequencing platforms and advanced microfluidic technologies.
• Drive Experimentation: Independently plan and execute complex laboratory experiments, troubleshoot technical challenges, and apply a rigorous, data-driven approach to optimization.
• Collaborate Across Disciplines: Partner with engineering, bioinformatics, and software teams to guide pipeline development and interpret deep sequencing data.
• Document & Protect Innovation: Maintain detailed laboratory records, develop standard operating procedures (SOPs), and contribute to intellectual property filings and regulatory submissions.

WHERE YOU WILL WORK

• Location: Work on-site at our San Jose, California location.
• Work Environment: Perform hands-on laboratory research while collaborating closely with cross-functional R&D teams.
• Travel: Occasional travel may be required based on business needs.

WHAT YOU WILL BRING US

• NGS Expertise: 0–5 years of hands‑on experience with advanced next‑generation sequencing platforms.
• Sequencing Workflow Development: 2–5 years of experience designing and optimizing novel sample arraying and sequencing workflow strategies for different applications.
• Platform & Microfluidics Experience: 2–5 years of experience evaluating, benchmarking, and integrating emerging sequencing platforms and advanced microfluidic technologies.
• Technical Knowledge: Deep understanding of surface chemistry, nucleic acid modifications, enzymatic assays, and PCR/RCR optimization.
• Scientific Research & Development: Track record of scientific research and experimental development demonstrated through publications, patents, or development of novel assays, workflows, or methods.
• Cross-Functional R&D Experience: Experience collaborating across scientific and technical disciplines on R&D projects involving sequencing workflow development, assay optimization, or platform integration.

ABOUT YOU

• Creative: You enjoy developing new approaches to challenging scientific and technical problems.
• Independent: You can take ownership of complex experiments while applying a rigorous, data-driven approach.
• Collaborative: You communicate effectively and enjoy working across molecular biology, chemistry, engineering, bioinformatics, and software disciplines.
• Innovative: You are motivated by developing new sequencing technologies and translating scientific concepts into applications.

WHAT YOUR EDUCATION LOOKS LIKE

• Education: Ph.D. in Molecular Biology, Genetics, Biochemistry, Bioengineering, Chemical Engineering, or a highly related life sciences discipline.

HOW WE WILL REWARD YOU

The base salary range for this position is $90,000 to $110,000, commensurate with experience, qualifications, and job responsibilities.

This position is eligible for an annual bonus program to recognize and reward your contributions and performance.

• Wellness: Annual gym membership reimbursement to support your health and wellness.
• Employee Discounts: Employee discount program to help you save on products and services.

We offer eligible employees and their dependents (including domestic partners) a comprehensive and competitive benefits package. Complete Genomics contributes significantly toward employee benefits coverage.

Benefits include:

• Medical, Dental, and Vision Coverage
• Life and AD&D Insurance
• Long-term and Short-term Disability Insurance
• Voluntary Life and AD&D Insurance
• Health Savings Account (HSA)
• Flexible Spending Accounts (FSA)
• Domestic Partner Benefits
• Commuter Program
• Employee Assistance Program
• 401(k) Retirement Plan
• Education Assistance
• 20 PTO days and 11 paid holidays per year

Complete Genomics provides equal employment opportunity without regard to race, color, religion, sex, national origin, sexual orientation, gender identity and/or expression, age, disability, veteran or uniformed service status, or any other characteristic protected by applicable law.