Biologics Developability & Preformulation Scientist

Sarepta Therapeutics; Columbus (OH); On-site; USD 106,400 - 133,000; Full time

Benefits offered by this job

Equal Opportunity Employer

e‑Verify participation

Job summary

Sarepta Therapeutics in Columbus, Ohio, seeks a seasoned Biologics Formulation Scientist to lead formulation experiments and stability studies for key intermediates and final products. You will develop developability profiles, optimize routes, and collaborate across teams to ensure scalable, compliant processes. The role requires Ph.D.

with 3–5 years or M.S. with 6–8 years in biologics formulation, with hands-on use of protein formulation tech and analytical assays.

Qualifications

• Ph.D. with 3–5 years biologics formulation experience or M.S. with 6–8 years.
• Experience with biologics formulation (e.g., mAbs) is required.
• Experience with AOCs or antibody‑drug conjugates (ADCs) formulation is a plus.
• Hands‑on experience with protein formulation technologies and stability/analytical assays.

Responsibilities

• Plan and execute formulation experiments to assess stability of intermediates and final products throughout manufacturing.
• Establish developability profiles for candidate molecules considering route-of-administration.
• Identify formulation-relevant QC attributes and guide stability-indicating assay development.
• Contribute technical recommendations on formulation technologies and instrumentation.
• Support cross-functional teams with product handling and storage recommendations.
• Prepare and review methods, protocols, and technical reports for regulatory submissions or technology transfer.
• Train and support Research Associates in experimental execution, troubleshooting, and data interpretation.

Skills

Biochemistry

Biochemical Engineering

Protein formulation

DoE principles

Cross-functional collaboration

Statistical/data analysis (JMP/Graph)

Excellent communication

Education

Ph.D. in Biochemistry/related formulation field

M.S. in Biochemistry/related field

Tools

Unchained Labs Big Tuna/Big Kahuna/Junior

Sartorius AMBR Crossflow

Pendotech 5TFF

Repligen KR2i

Job description

Sarepta Therapeutics in Columbus, Ohio, seeks a seasoned Biologics Formulation Scientist to lead formulation experiments and stability studies for key intermediates and final products. You will develop developability profiles, optimize routes, and collaborate across teams to ensure scalable, compliant processes. The role requires Ph.D.

with 3–5 years or M.S. with 6–8 years in biologics formulation, with hands-on use of protein formulation tech and analytical assays.