Senior Scientist, Protein Formulation & Biophysics

Pfizer

Andover (MA)

On-site

USD 106,000 - 177,000

Full time

14 days+

Application generator

Don’t send a generic resume — generate a resume and cover letter tailored to this exact role.

Get past ATS filters

Benefits offered by this job

Relocation assistance

Pfizer Benefits

Job summary

Pfizer is seeking a Principal Scientist to lead formulation science and biophysical characterization for high-concentration biologics, driving innovations for subcutaneous delivery. You will design studies, translate mechanistic insights into scalable solutions, and collaborate across cross-functional teams.

The role emphasizes hands-on formulation work, exposure to biophysical analyses, and leadership of platform initiatives within a dynamic biologics group.

Qualifications

PhD in relevant field with 3–5 years in biologics formulation or related areas.
Demonstrated scientific output preferred (publications/conferences).
Strong hands-on experience with biophysical/analytical techniques and multi‑technique data interpretation.

Responsibilities

Design and optimize protein formulations for biologics across modalities.
Apply biophysical/physicochemical characterization to assess risks (aggregation, viscosity, stability).
Develop innovative formulation strategies and scalable workflows.
Collaborate with cross-functional teams to implement new technologies.
Lead cross-functional efforts for subcutaneous delivery and provide regulatory input as needed.

Skills

Protein formulation

Biophysical characterization

Parenteral delivery

Data analysis

Cross-functional collaboration

Education

PhD in Pharmaceutics/Pharmaceutical Sciences

Tools

DLS

DSC

SEC‑MALS

Job description

The role emphasizes hands-on formulation work, exposure to biophysical analyses, and leadership of platform initiatives within a dynamic biologics group.

Get your free, confidential resume review.

or drag and drop your file here.