Bio-Analytical Co-op-Northeastern Students

Seaport Therapeutics; Boston (MA); On-site; USD 25,000 - 30,000; Part time

Job summary

Seaport Therapeutics in Boston is seeking a lab-based bioanalytical co-op focused on LC-MS to support the Discovery team's preclinical work. The successful candidate will work on in vitro screenings of lipid prodrugs and contribute to method development for quantitative and qualitative analyses.

The role offers exposure to a startup environment, collaboration with multidisciplinary scientists, and hands-on experience with chromatography, mass spectrometry, and data reporting while documenting

Qualifications

• Enrolled in a Master’s program in Chemistry, Biochemistry, or related field.
• Lab/co-op experience preferred.
• Knowledge of HPLC, LC-MS, and analytical techniques.
• Strong organizational skills and attention to detail.

Responsibilities

• Execute in vitro experiments using LC-MS for screening lipid prodrugs.
• Process and analyze samples to generate data for prodrugs (DMPK focus).
• Contribute to LC-MS method development for quantitative/qualitative analyses.
• Routine use and troubleshooting of LC-MS instrumentation.
• Document all experiments using an electronic notebook and analyze data for reports.

Skills

Lab skills

Mass spectrometry

HPLC

Chromatography

Data analysis

Documentation

Teamwork

Attention to detail

Education

Master's student in Chemistry/Biochemistry/Pharmacy

Tools

LC-MS

HPLC

Job description

Bio-Analytical Co-op-Northeastern Students

Seaport Therapeutics is a clinical-stagetherapeuticscompany advancing the development of novel neuropsychiatric medicines in areas of high unmet patient needs. The Company has a proven strategy of advancing clinically validated mechanisms previously held back by limitations that are overcome with its proprietaryGlyphTMtechnology platform. All the therapeutic candidates in its pipeline of first and best-in-class medicines are based on the Glyph platform, which is uniquely designed to enable oral bioavailability, bypass first-passmetabolismand reduce hepatotoxicity and other side effects. Seaport is led by an experienced team that invented and advanced important neuropsychiatric medicines and areguided by an extensive network of renowned scientists,cliniciansand key opinion leaders. For more information, please visitwww.seaporttx.com .

Job Description

Seaport Therapeutics is seeking a co-op student for a lab-based bioanalysis position to be part of our Discovery team. This co-op will have a focus on LC-MS to assist in the screening of novel drugs. We are looking for a highly motivated individual who is looking to be a part of a multidisciplinary team and to gain experience in a startup environment. This position will contribute to advancing the pipeline of impactful candidates generated from our novel Glyph™ prodrug platform.

Some of the responsibilities will include:

• Executing in vitro experiments, using LC-MS, for the screening of lipid prodrugs to support preclinical discovery
• Processing and analyzing in vivo samples (plasma, lymph fluid, etc.) to generate DMPK data for various prodrugs
• Contributing to the development and optimization of LC-MS methods for both quantitative and qualitative analysis
• Routine use and troubleshooting of LC-MS instrumentation
• Documenting all experiments using an electronic notebook and analyzing data for reports and regular internal presentations

Experience and Skills

• Enrolled in a Chemistry, Biochemistry, Pharmaceutical Sciences, Chemical Engineering, or related program at the Master’s Level
• Previous Co-op or lab experience is preferred
• Knowledge of or experience with: HPLC, reverse phase chromatography, mass spectrometry instrumentation, enzyme kinetics, protein precipitation, liquid-liquid extraction
• Strong organizational skills, attention to detail, and eagerness to learn.