Bench Scientist

Pioneer Data; Andover (MA); On-site; USD 70,000 - 90,000; Full time

Job summary

Pioneer Data in Andover, Massachusetts, seeks a Bioanalytical Scientist for its protein mass spectrometry lab, focusing on the development of sensitive quantitative assays. The role involves all phases of lab operations, including assay execution, instrument maintenance, and data analysis.

The ideal candidate will have expertise in bioanalytical processes, particularly in protein biochemistry and triple quadrupole mass spectrometry. Passion for new learning and method development is essential.

Qualifications

• Expertise in bioanalytical procedures, particularly immunoanalytical workflows.
• Solid background in protein biochemistry.
• Experience with quantitative mass spectrometry.

Responsibilities

• Develop sample preparation methods and execute assays.
• Maintain and troubleshoot mass spectrometry instruments.
• Analyze LC-MS/MS data using bioinformatics tools.

Skills

Protein biochemistry

Immunoanalytical workflows

Triple quadrupole mass spectrometry

Tools

Bioinformatics software

Quantitation software

Liquid handling robotics

Job description

• A rare position is available for a bioanalytical scientist to join a state-of-the-art protein mass spectrometry laboratory lab in Pharmaceutical's Pharmacokinetics Dynamics and Metabolism department.
• The lab based role will focus on the development of a Client type of sensitive quantitative assay to characterize and quantify the effect of anti-drug antibodies against protein bio therapeutics in the context of unwanted immunogenicity.
• This position requires expertise in bioanalytical procedures including immunoanalytical workflows, solid background in protein biochemistry, and ideally expertise in triple quadrupole quantitative mass spectrometry.
• The candidate will participate in all phases of mass spec laboratory operations including the development of sample preparation methods, assay execution, instrument maintenance and data analysis/reporting. We are looking for a scientist passionate about learning and quickly applying new skills to the project needs.

Additional Skills:

• Apply existing protein quantitation workflows using bead and column based immunoaffinity enrichment including the use of liquid handling robotics.
• Run bioanalytical assays under minimal supervision; initiative in method development is expected.
• Independent daily operation, calibration, maintenance, and trouble shooting of multi-dimensional nanoflow liquid chromatography and nanospray triple quadrupole mass spectrometry instrumentation.
• Support analysis of quantitative LC-MS/MS data using relevant bioinformatics and quantitation software.

Additional Information

All your information will be kept confidential according to EEO guidelines.