Associate Scientist, Cell-Based HTS & Gene Editing

ClinLab Solutions Group; Boston (MA); On-site; USD 110,000 - 170,000; Full time

Job summary

ClinLab Solutions Group seeks a skilled scientist to design, execute, and analyze cell-based assays and high-throughput screening workflows, advancing genomic engineering platforms. The role requires strong technical and data analysis skills and collaboration across cross-functional teams.

You will design and implement assays, develop screening campaigns, troubleshoot protocols, and communicate results clearly to scientific colleagues, aiding progression of optimized candidates into development

Qualifications

• Bachelor’s degree in cell biology, molecular biology, or related field with 5+ years of relevant experience, or a Master’s degree with 3+ years of experience.
• Experience in high-throughput cell-based screening, preferably with primary T cells, hepatocytes, and cancer cell lines.
• Hands-on expertise with gene editing technologies (CRISPR nucleases, recombinases, base editors, or transcriptional effectors).
• Familiarity with laboratory automation platforms for cell-based screening workflows.
• Proficiency in nucleic acid QC methods such as TapeStation, Qubit, NanoDrop, and qPCR.
• Demonstrated ability to independently generate precise, reproducible data and conduct rigorous quantitative analysis.
• Strong organizational skills for managing complex datasets and multiple projects.
• Excellent written and verbal communication skills, with the ability to present complex technical information clearly.

Responsibilities

• Design and implement cell-based assays and screening workflows to support platform and program goals, both independently and collaboratively.
• Develop and execute high-throughput arrayed and pooled screening campaigns with a focus on rigor and reproducibility.
• Troubleshoot experimental protocols, analyze data, and convert findings into actionable scientific insights.
• Maintain comprehensive laboratory records and effectively communicate results to scientific colleagues.
• Collaborate with cross-functional teams to facilitate the progression of optimized candidates into further development stages.
• Utilize gene editing technologies, such as CRISPR nucleases, recombinases, base editors, or transcriptional effectors, in experimental workflows.
• Apply laboratory automation platforms and nucleic acid quality control methods, including TapeStation, Qubit, NanoDrop, and qPCR.
• Manage complex datasets, prioritize overlapping projects, and present technical information clearly to diverse audiences.

Skills

Experimental design

Data analysis

Collaboration

Scientific communication

Education

Bachelor’s degree in cell biology or molecular biology

Master’s degree in related field

Tools

CRISPR nucleases

Recombinases

Base editors

Transcriptional effectors

TapeStation

Qubit

NanoDrop

qPCR

Job description

ClinLab Solutions Group seeks a skilled scientist to design, execute, and analyze cell-based assays and high-throughput screening workflows, advancing genomic engineering platforms. The role requires strong technical and data analysis skills and collaboration across cross-functional teams.

You will design and implement assays, develop screening campaigns, troubleshoot protocols, and communicate results clearly to scientific colleagues, aiding progression of optimized candidates into development