Associate Research Scientist

TechDigital Group; Cambridge (MA); On-site; USD 70,000 - 100,000; Full time

Job summary

An innovative research center is looking for a dedicated Associate Scientist to join their dynamic drug discovery team in Cambridge. This role involves developing and optimizing cellular assays to characterize and advance client molecules, contributing significantly to cutting-edge oncology programs. The ideal candidate will have a strong background in preclinical laboratory work, particularly in mammalian cell culture, and will thrive in a collaborative environment. If you are self-motivated and eager to make impactful contributions to drug discovery, this is an exciting opportunity to be part of a forward-thinking organization at the forefront of cancer research.

Qualifications

• 4+ years of practical experience in preclinical laboratory work.
• Strong hands-on experience in mammalian cell culture and aseptic techniques.

Responsibilities

• Develop and execute mechanistic in vitro cellular assays for drug discovery.
• Collaborate cross-functionally to advance oncology programs.

Skills

Mammalian cell culture

Aseptic technique

Experimental design

Data analysis

Communication skills

Time management

Education

Bachelor's degree in Biology

Bachelor's degree in Molecular/Cell Biology

Bachelor's degree in Biochemistry

Tools

Microsoft Office

Electronic notebooks

Mosaic database

Job description

The Mechanism of Cancer Resistance (MoCR) Thematic Research Center (TRC) is seeking a highly motivated Associate Scientist to support Discovery Biology research programs at our facility in Cambridge, MA. The ideal candidate will contribute to our discovery pipeline from the bench by taking responsibility for developing, optimizing, and troubleshooting cellular assays to characterize and advance Client molecules of interest. We are currently seeking a candidate with 4+ years of practical experience in preclinical laboratory work. The ideal candidate will thrive in a collaborative environment and make meaningful contributions as a valued member of our dynamic drug discovery team. Key attributes will include strong organizational skills, a proven track record of high productivity, and excellent communication and interpersonal abilities.

Job Responsibilities include:
• Working both independently and collaboratively to support cutting-edge Oncology drug discovery biology programs.
• Develop and execute mechanistic in vitro cellular assays to characterize mechanism of action of Client compounds.
• Cell culture maintenance, cryopreservation, validation, and inventory management.
• Maintain detailed and organized records of protocols and experimental results.
• Collaborate cross-functionally with other team members to advance programs.
• Analyze, interpret, and present experimental data in team meetings.

Job Qualifications and Requirements
• Bachelor's degree in Biology, Molecular/Cell Biology, biochemistry or a related discipline, with 4+ years of relevant work experience.
• Strong hands-on experience in mammalian cell culture including expertise in aseptic technique, culture optimization, cell counting, cryopreservation, and validation methods.
• Experience in managing or supporting cell banking, and familiarity with databases such as Mosaic, would be a plus but not required.
• Proficiency in experimental design, data analysis, and a range of biology skill sets including in vitro cell assay development, plate-based assays, Western blotting, protein quantification, ELISA, MSD, transfections, lentiviral transductions, siRNA/shRNA/CRISPR, qPCR, and viability assays.
• Excellent communication skills, both verbal and written, with the ability to work effectively both independently and as part of a cross-functional collaborative team.
• Strong proficiency in workload planning, prioritization, organization, time management, meticulous attention to detail, and consistent follow-through.
• Experience utilizing electronic notebooks is preferred, and basic proficiency in Microsoft Office is required.
• Self-motivated, adaptable, eager to develop new skills, and possesses a positive attitude.