Associate Director, Global Proteomics

Johnson Johnson; Cambridge (MA); On-site; USD 180,000 - 240,000; Full time

Job summary

Johnson & Johnson in Cambridge, MA, seeks an Associate Director of Global Proteomics to lead a wet-lab proteomics team within the Discovery Proteomic Platforms group. You will drive MS operations, implement delivery frameworks, and collaborate across multiomics to guide target identification and therapeutic optimization.

The role emphasizes scientific leadership, cross-functional partnership with Oncology, Immunology, and Neuroscience, and the translation of complex data into actionable program

Qualifications

• PhD in a relevant field required.
• 8+ years hands-on proteomics lab experience, 4+ years in drug discovery.
• Proven track record leading mass spectrometry operations with portfolio impact.

Responsibilities

• Managing and developing a wet-lab team with a culture of scientific excellence and safety.
• Establishing delivery frameworks with SLAs, cycle-time targets, and prioritization aligned to portfolio decisions.
• Overseeing proteomics studies for target ID/validation, MoA elucidation, biomarker discovery, and therapeutic optimization.
• Partnering with bioinformatics/data science to ensure QC and FAIR data practices, plus AI-enabled data interpretation.
• Collaborating across multiomics to design integrated studies and interpret proteomic data with other readouts.
• Translating proteomics findings for governance forums to influence study design and portfolio strategy.
• Shaping platform priorities and roadmap to balance portfolio delivery and new capabilities.

Skills

Proteomics leadership

Mass spectrometry operations

Team leadership

Data interpretation

Education

Doctorate in Analytical Chemistry/Biochemistry/Pharmacology

Tools

LC/MS platforms

Thermo Orbitrap Exploris

Orbitrap Eclipse

Orbitrap Fusion Lumos

Bruker timsTOF

Job description

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at jnj.com

As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit.

Job Function

Discovery & Pre-Clinical/Clinical Development

Job Sub Function

Biological Research

Job Category

People Leader

All Job Posting Locations

Cambridge, Massachusetts, United States of America

Job Description

About Innovative Medicine. Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

Learn more at https://www.jnj.com/innovative-medicine

We are searching for the best talent for an Associate Director, Global Proteomics to be located in Cambridge, MA.

Do you want to use your hard earned skills and drive to make a difference in the lives of patients? This team and platform lead role combines scientific depth, operational leadership, and strong cross functional collaboration to deliver across the Johnson & Johnson portfolio. The candidate will lead Global Proteomics, one of three platform pillars within the Discovery Proteomic Platforms (DPP) group - alongside Chemoproteomics and Immunopeptidomics - in the Discovery Technologies and Molecular Pharmacology (DTMP) department of Therapeutics Discovery.

Lead a motivated team dedicated to deploying groundbreaking mass spectrometry proteomics technologies as we, together, tackle the challenges of target identification and validation as well as therapeutic optimization. Work across a leading multiomics organization to provide integrated insights across a variety of 'omics layers. Your team's data shapes study design, compound selection, and program direction across a broad portfolio with influence earned through scientific rigor and partnership with program teams across Oncology, Immunology, and Neuroscience. Work in an exciting, interdisciplinary environment, overlapping the different stages of the discovery pipeline. With your help, we will drive development of medicines for our patients!

You will be responsible for

• Managing and developing a team of wet‑lab scientists; build an inclusive, feedback‑rich culture focused on scientific excellence, safety, and continuous improvement.
• Establishing delivery frameworks with clear SLAs , cycle‑time targets, and prioritization aligned to portfolio decision points and pre‑portfolio (platform‑building) needs.
• Planning, overseeing, and performing/providing oversight for proteomics studies supporting target ID/validation, MoA elucidation, biomarker discovery, and therapeutic optimization.
• Partnering closely with bioinformatics/data science to ensure robust QC, FAIR data practices, and decision‑ready analyses as well as to apply computational and AI-enabled approaches to proteomic data interpretation and decision support.
• Partnering across the multiomics organization to design integrated studies and interpret proteomic data alongside transcriptomic, genomic, and spatial readouts, delivering conclusions no single layer supports on its own.
• Translating sophisticated proteomics findings for non‑experts and governance forums; influence study design and portfolio strategy across biology, chemistry, biologics, safety, DMPK, and clinical translation.
• Shaping the platform's priorities and roadmap, balancing sustained portfolio delivery with investment in new capability.

Qualifications / Requirements

Education

• A Doctorate (in Analytical Chemistry, Biochemistry, Molecular Biology, Pharmacology or a related field) is required

Experience and Skills

• 8+ years of hands‑on experience in a proteomics laboratory, including 4+ years in a drug discovery setting.
• Proven track record leading mass spectrometry operations (people, platforms, and processes) with measurable portfolio impact.
• Hands‑on proficiency with LC and MS platforms , including (examples, not exhaustive): LC: Waters ACQUITY/nanoACQUITY, Thermo Vanquish Neo , Evosep One, Dionex UltiMate 3000 MS: Thermo Orbitrap Exploris , Orbitrap Eclipse , Orbitrap Fusion Lumos ; Bruker timsTOF
• Proficiency in automated, plate-based proteomic workflows and