Associate Director, Global Proteomics

6084-Janssen Research & Development, LLC Legal Entity

Cambridge (MA)

On-site

USD 137,000 - 236,000

Full time

4 days ago

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Job summary

Johnson & Johnson in Cambridge, MA is seeking an Associate Director, Global Proteomics to lead a world-class proteomics team and advance mass spectrometry capabilities across discovery to translation.

The role blends scientific depth with cross-functional leadership, setting strategy, delivering on SLAs, and partnering with bioinformatics to drive data-driven decisions across Oncology, Immunology, and Neuroscience.

Qualifications

Requires a Doctorate in Analytical Chemistry, Biochemistry, Molecular Biology, Pharmacology or related field.
8+ years hands-on proteomics lab experience; 4+ years in drug discovery setting.

Responsibilities

Lead wet-lab scientists and develop a high-performing proteomics team.
Establish delivery frameworks with clear SLAs and timelines.
Oversee proteomics studies for target ID/validation and MoA elucidation.
Collaborate with bioinformatics and data science for QC, FAIR data, and analyses.
Translate complex proteomics findings to non-experts and governance forums.

Skills

Team leadership

Mass spectrometry

LC-MS platforms

Cross-functional collaboration

Data interpretation

Project coordination

Education

PhD in analytical chemistry

Tools

LC-MS platforms

Job description

Associate Director, Global Proteomics

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at jnj.com As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit.

Job Function: Discovery & Pre-Clinical/Clinical Development Job Sub Function: Biological Research Job Category: People Leader All Job Posting Locations: Cambridge, Massachusetts, United States of America

We are searching for the best talent for an Associate Director, Global Proteomics to be located in Cambridge, MA. Do you want to use your hard earned skills and drive to make a difference in the lives of patients? This team and platform lead role combines scientific depth, operational leadership, and strong cross functional collaboration to deliver across the Johnson & Johnson portfolio. The candidate will lead Global Proteomics, one of three platform pillars within the Discovery Proteomic Platforms (DPP) group — alongside Chemoproteomics and Immunopeptidomics — in the Discovery Technologies and Molecular Pharmacology (DTMP) department of Therapeutics Discovery. Lead a motivated team dedicated to deploying groundbreaking mass spectrometry proteomics technologies as we, together, tackle the challenges of target identification and validation as well as therapeutic optimization. Work across a leading multiomics organization to provide integrated insights across a variety of 'omics layers. Your team's data shapes study design, compound selection, and program direction across a broad portfolio with influence earned through scientific rigor and partnership with program teams across Oncology, Immunology, and Neuroscience. Work in an exciting, interdisciplinary environment, overlapping the different stages of the discovery pipeline. With your help, we will drive development of medicines for our patients!

You will be responsible for:

Managing and developing a team of wet‑lab scientists
build an inclusive, feedback‑rich culture focused on scientific excellence, safety, and continuous improvement.
Establishing delivery frameworks with clear SLAs, cycle‑time targets, and prioritization aligned to portfolio decision points and pre‑portfolio (platform‑building) needs.
Planning, overseeing, and performing/providing oversight for proteomics studies supporting target ID/validation, MoA elucidation, biomarker discovery, and therapeutic optimization.
Partnering closely with bioinformatics/data science to ensure robust QC, FAIR data practices, and decision‑ready analyses as well as to apply computational and AI‑enabled approaches to proteomic data interpretation and decision support.
Partnering across the multiomics organization to design integrated studies and interpret proteomic data alongside transcriptomic, genomic, and spatial readouts, delivering conclusions no single layer supports on its own.
Translating sophisticated proteomics findings for non‑experts and governance forums; influence study design and portfolio strategy across biology, chemistry, biologics, safety, DMPK, and clinical translation.
Shaping the platform's priorities and roadmap, balancing sustained portfolio delivery with investment in new capability.

Qualifications / Requirements:

Education: A Doctorate (in Analytical Chemistry, Biochemistry, Molecular Biology, Pharmacology or a related field) is required
Experience and Skills: Required: 8+ years of hands‑on experience in a proteomics laboratory, including 4+ years in a drug discovery setting.
Proven track record leading mass spectrometry operations (people, platforms, and processes) with measurable portfolio impact.
Hands‑on proficiency with LC and MS platforms, including (examples, not exhaustive): LC: Waters ACQUITY/nanoACQUITY, Thermo Vanquish Neo, Evosep One, Dionex UltiMate 3000 MS: Thermo Orbitrap Exploris, Orbitrap Eclipse, Orbitrap Fusion Lumos; Bruker timsTOF
Proficiency in automated, plate-based proteomic workflows and a track record of partnering with automation and engineering specialists to implement and scale them (e.g., Beckman Biomek, Hamilton Microlab STAR, TECAN Fluent, Dynamic Devices Lynx).
Strong program and portfolio coordination skills; ability to manage multiple priorities, set SLAs, and deliver on time.
Familiarity with machine learning or AI‑enabled approaches applied to mass spectrometry data (spectral prediction, DIA search, automated QC and analysis) and comfort partnering with experts to evaluate and adopt.
Excellent interpersonal skills working with diverse colleagues and proven ability to translate complex technical issues into clear language for any audience from scientists to executives.
Preferred: Experience leading a shared platform, core, or centralized capability in a matrixed R&D organization.
Preferred: Demonstrated success operating within an established technical organization adopting and building on existing platforms, standards, and specialist expertise.
Preferred: Exposure to single‑cell proteomics, spatial proteomics, protein–protein interaction mapping, and/or limited‑sample workflows.
Preferred: Record of scientific innovation (publications, patents) and external visibility (ASMS, HUPO presentations).
Preferred: Knowledge of fit‑for‑purpose quality systems (e.g., GLP‑adjacent discovery practices), laboratory information management systems (LIMS), and FAIR data principles.

The expected base pay range for this position is $137,000 to $235,750. The Company maintains highly competitive, performance-based compensation programs. Under current guidelines, this position is eligible for an annual performance bonus in accordance with the terms of the applicable plan. The annual performance bonus is a cash bonus intended to provide an incentive to achieve annual targeted results by rewarding for individual and the corporation’s performance over a calendar/performance year. Bonuses are awarded at the Company’s discretion on an individual basis. Subject to the terms of their respective plans, employees and/or eligible dependents are eligible to participate in the following Company sponsored employee benefit programs: medical, dental, vision, life insurance, short- and long-term disability, business accident insurance, and group legal insurance.

Subject to the terms of their respective plans, employees are eligible to participate in the Company’s consolidated retirement plan (pension) and savings plan (401(k)).

Time off benefits:

Vacation -120 hours per calendar year
Sick time - 40 hours per calendar year
for employees who reside in the State of Washington -56 hours per calendar year
Holiday pay, including Floating Holidays -13 days per calendar year
Work, Personal and Family Time - up to 40 hours per calendar year
Parental Leave - 480 hours within one year of the birth/adoption/foster care of a child
Condolence Leave - 30 days for an immediate family member: 5 days for an extended family member
Caregiver Leave - 10 days
Volunteer Leave - 4 days
Military Spouse Time-Off - 80 hours

Additional information can be found through the link below. For additional general information on Company benefits, please go to: https://www.careers.jnj.com/employee-benefits

This job posting is anticipated to close on XX/XXXX. The Company may, however, extend this time-period, in which case the posting will remain available on https://www.careers.jnj.com to accept additional applications.

Johnson & Johnson is an Equal Opportunity Employer.

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law.

We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants’ needs. If you are an individual with a disability and would like to request an accommodation, external applicants please contact us via https://www.jnj.com/contact-us/careers, internal employees contact AskGS to be directed to your accommodation resource.

Preferred Skills: