Associate Director, Expression Sciences

Scorpion Therapeutics; Spring House (PA); On-site; USD 150,000 - 210,000; Full time

Job summary

Johnson & Johnson is seeking an Associate Director of Expression Sciences based in Spring House, PA. You will lead teams responsible for recombinant expression across bacterial, insect, and mammalian systems to accelerate drug discovery.

The role requires strategic oversight of automation, platform development, and workflows for challenging targets, including membrane proteins, with a focus on integration of AI/ML to enhance screening and data analysis.

Qualifications

• Ph.D. in Biochemistry, Molecular or Structural Biology, Chemical Engineering, or related field with 10+ years industry experience.
• Deep expertise in recombinant expression across multiple systems.
• Proven leadership in managing scientific teams.
• Strong collaboration skills with structural biology and discovery teams.
• Excellent communication.

Responsibilities

• Manage and mentor teams conducting high-throughput expression screening across bacterial, insect, and mammalian systems.
• Define strategic vision for automation and platform development.
• Design screening workflows for challenging targets, including membrane proteins.
• Implement new technologies like AI/ML-guided screening.
• Oversee data analysis and vendor relationships.
• Ensure regulatory compliance.

Skills

Recombinant expression

Leadership

Cross-functional collaboration

Communication

Education

PhD in Biochemistry / Molecular or Structural Biology / Chemical Engineering

Tools

LIMS

AI/ML integration

Job description

Role: Associate Director of Expression Sciences at Johnson & Johnson, leading efforts in recombinant protein expression to support drug discovery.

Responsibilities

• manage and mentor teams conducting high-throughput expression screening across bacterial, insect, and mammalian systems;
• define strategic vision for automation and platform development;
• design screening workflows for challenging targets, including membrane proteins;
• implement new technologies like AI/ML-guided screening;
• oversee data analysis and vendor relationships;
• ensure regulatory compliance.

Qualifications

• Ph.D. in Biochemistry, Molecular or Structural Biology, Chemical Engineering, or related field with 10+ years industry experience;
• deep expertise in recombinant expression across multiple systems;
• proven leadership in managing scientific teams;
• strong collaboration skills with structural biology and discovery teams;
• excellent communication.

Preferred: experience with membrane protein expression, AI/ML integration, LIMS implementation, and a track record of publications or patents.

High-Value: focus on protein expression for drug discovery, including biophysical and structural applications, supporting Innovative Medicine pipeline.

Work Setup

Based in Spring House, PA, with an emphasis on collaborative, fast-paced environment.