Associate Director, Computational Sciences — Biotherapeutics Portfolio Group Lead

Scorpion Therapeutics; Cambridge (MA); On-site; USD 212,000 - 257,000; Full time

Benefits offered by this job

Flexible Time Off

Comprehensive health insurance

Paid time off

Job summary

Scorpion Therapeutics, located in Cambridge, MA, seeks a senior leader to drive computational sciences across biologics programs in the pre-clinical stage. You will guide a portfolio team, applying bioinformatics, machine learning, and AI-enabled design to optimize antibody discovery and experimental decision-making.

You will partner with project teams to translate scientific questions into computational strategies, determine actionability of predictions, and mentor junior scientists to elevate

Qualifications

• Bachelor's, Master's, or PhD in a relevant field with 8–12+ years combined experience.
• Advanced degree preferred in computational biology/chemistry, bioengineering, biophysics, ML, or related field.
• Experience leading teams and influencing project decisions through rigorous analysis and clear communication.

Responsibilities

• Lead a computational sciences portfolio team across multiple biologics programs in the pre-clinical pipeline.
• Apply bioinformatics, ML, and AI-enabled design to improve antibody selection, design, optimization, characterization, and experimental decision-making.
• Determine when computational predictions are actionable vs qualified vs requiring additional experimental evidence.
• Partner with project teams to translate scientific questions into computational strategies and decision-ready recommendations.
• Communicate hypotheses, methods, results, visualizations, and recommendations in governance-ready formats.
• Coach, mentor, and develop computational scientists; foster rigor, urgency, accountability, collaboration, and impact.

Skills

Leadership

Communication

Strategic thinking

Bioinformatics

Machine learning

Education

PhD in relevant field

Master's degree

Bachelor's degree

Tools

Computational biology tools

Biotech software experience

Job description

Responsibilities

• Lead a computational sciences portfolio team across multiple biologics programs in the pre-clinical pipeline.
• Apply bioinformatics, machine learning, and AI-enabled design to improve antibody selection, design, optimization, characterization, and experimental decision-making.
• Determine when computational predictions are actionable vs qualified vs requiring additional experimental evidence.
• Partner with project teams to translate scientific questions into computational strategies and decision-ready recommendations (from binder discovery through candidate nomination).
• Communicate hypotheses, methods, results, visualizations, and recommendations in tailored, governance-ready formats.
• Coach, mentor, and develop computational scientists; foster rigor, urgency, accountability, collaboration, and impact.

Qualifications

• Bachelor's (12+ years) OR Master's (10+ years) OR PhD (8+ years) in a relevant field.
• Preferred advanced degree in computational biology/chemistry, bioengineering, biophysics, machine learning, or related field; experience applying computational methods to biologics/protein engineering/antibody or therapeutic discovery.
• 4+ years leadership experience.
• Track record influencing project decisions through rigorous analysis and clear communication.
• Ability to prioritize computational effort across competing needs and timelines.
• Experience validating/calibrating models to experimental outcomes and communicating confidence/limitations.
• Strong understanding of discovery biotherapeutics workflows from binder discovery to candidate nomination.

Benefits & Pay (as stated)

Flexible Time Off and comprehensive health/insurance; U.S. ranges provided: Cambridge Crossing $211,950-$256,831; Princeton-NJ $184,300-$223,325; San Diego-CA $202,730-$245,665.