Analytical Development Research Associate: RNA/LNP

GenScript; Seattle (WA); On-site; USD 65,000 - 80,000; Full time

Benefits offered by this job

Onsite gym

Job summary

GenScript is seeking a Research Associate, Analytical Development in Seattle to support development, qualification, and routine execution of analytical methods for RNA, lipids, lipid nanoparticles (LNPs), and related bioconjugates. The role involves hands-on work with HPLC/UHPLC, LC-MS, nano flow cytometry, and RNA/LNP testing, collaborating with R&D, QC, and Production teams.

The successful candidate will perform method development, troubleshooting, and method transfer, contributing to

Qualifications

• Bachelor’s degree in Chemistry, Analytical Chemistry, Biochemistry, Biology, Biotechnology, Pharmaceutical Sciences, or a related field.
• 0-5 years of relevant lab experience, preferably in analytical chemistry or biopharmaceutical characterization.
• Hands-on experience with HPLC/UHPLC and/or LC-MS, including sample prep and data review.
• Practical experience with flow cytometry, including sample prep, controls, data acquisition, and interpretation.
• Strong wet-lab skills: accurate pipetting, buffer prep, dilution calculations, contamination control.
• Ability to follow procedures and maintain clear, traceable records; proficient with Excel or similar tools.
• Attention to detail, organization, problem solving, and ability to manage multiple batches while communicating progress.
• Ability to work collaboratively in a multidisciplinary R&D environment.

Responsibilities

• Perform chromatographic analyses and sample prep for RNA, lipids, LNPs, and related bioconjugates.
• Support LC-MS characterization of RNA, oligonucleotides, and related materials.
• Conduct RNA/LNP analytical development, including assays for concentration, purity, and integrity.
• Prepare samples and controls for nano flow cytometry and evaluate labeling/conjugation attributes.
• Execute routine wet-lab tasks, data processing, and generate clear data summaries.
• Assist with SOPs, method transfer, and cross-functional collaboration across R&D, QC, and Production.

Skills

HPLC/UHPLC

LC-MS

Flow cytometry

RNA/LNP analysis

Pipetting & dilutions

Data analysis (Excel)

Troubleshooting

Documentation

Education

Bachelor's degree in Chemistry or related field

Master's degree in Analytical Chemistry or related field (preferred)

Tools

Empower

Xcalibur

CytoFLEX

RNA analysis software

Job description

GenScript is seeking a Research Associate, Analytical Development in Seattle to support development, qualification, and routine execution of analytical methods for RNA, lipids, lipid nanoparticles (LNPs), and related bioconjugates. The role involves hands-on work with HPLC/UHPLC, LC-MS, nano flow cytometry, and RNA/LNP testing, collaborating with R&D, QC, and Production teams.

The successful candidate will perform method development, troubleshooting, and method transfer, contributing to