AI-Driven Modeling Engineer for Neurodegenerative Systems

Go Fractional; South San Francisco (CA); Remote; USD 120,000 - 170,000; Full time

Benefits offered by this job

Equity opportunity

Contract-to-Hire

Remote-friendly

Job summary

Go Fractional is seeking a highly skilled modeling-focused professional to expand an AI-driven BHN platform. You will work at the intersection of computational biology and systems engineering, blending scientific modeling with engineering implementation.

The role emphasizes hands-on development of mechanistic ODE models, collaboration with software engineers, and the creation of clear model documentation. Flexible location with travel to South San Francisco as needed.

Qualifications

• Advanced degree in systems biology, biomedical/chemical engineering, computational biology, or related quantitative field.
• Experience developing ODE-based models of complex nonlinear systems.
• Hands-on experience using AI tools to support model development and analysis.
• Strong scientific communication across the science–engineering boundary.

Responsibilities

• Extend depth and breadth of the BHN model, including expansion into additional neurodegenerative diseases.
• Develop and refine ODE-based mechanistic models of biological processes.
• Use the BHN model to analyze target opportunities and support therapeutic development and experiments.
• Collaborate with software developers in AI-driven workflows and tooling to accelerate model development and analysis.
• Create clear annotations and documentation of model and software architecture and code.

Skills

ODE-based modeling

AI tools usage

Scientific communication

Cross-disciplinary collaboration

Education

PhD or MS with relevant experience

Tools

Mathematica

Job description

Go Fractional is seeking a highly skilled modeling-focused professional to expand an AI-driven BHN platform. You will work at the intersection of computational biology and systems engineering, blending scientific modeling with engineering implementation.

The role emphasizes hands-on development of mechanistic ODE models, collaboration with software engineers, and the creation of clear model documentation. Flexible location with travel to South San Francisco as needed.