AI-Driven Clinical PK Lead for Transformative Medicines

Novartis Group Companies; Cambridge (MA); On-site; USD 186,000 - 345,000; Full time

Job summary

Novartis Group of Companies in Cambridge, MA seeks a PK Sciences leader to define and lead AI-enabled strategies for clinical pharmacology, transforming how data supports decision-making across development.

You will collaborate with ADME, M&S, and clinical teams to deliver AI-driven PK/PD insights, drive automation, and support regulatory submissions while guiding translational medicine strategies.

Qualifications

• Ph.D. / Pharm.D. with relevant clinical pharmacology experience.
• 8–10 years in drug discovery/development; 6+ years in lead ADME/DMPK or AI strategy.
• Extensive PK knowledge including PK/PD, drug metabolism, and regulatory awareness.
• Strong oral and written communication skills.

Responsibilities

• Lead the development and oversee implementation of AI strategy for clinical pharmacology within PKS.
• Advise on AI-enabled strategies to transform PKS deliverables across development, from preclinical to regulatory submissions.
• Collaborate with PK Sciences, Drug Disposition, and Modeling & Simulation teams to integrate PKS insights into project plans.
• Identify high-value AI use cases to improve planning, analyses, and decision quality in pharmacology.
• Partner with clinicians and development colleagues to align PKS insights with study design and interpretation.

Skills

Clinical Pharmacology

Pharmacokinetics

AI Strategy

Drug Development

Translational Medicine

Cross-functional Collaboration

Communication Skills

Regulatory Science

Education

Ph.D./Pharm.D.

Job description

Novartis Group of Companies in Cambridge, MA seeks a PK Sciences leader to define and lead AI-enabled strategies for clinical pharmacology, transforming how data supports decision-making across development.

You will collaborate with ADME, M&S, and clinical teams to deliver AI-driven PK/PD insights, drive automation, and support regulatory submissions while guiding translational medicine strategies.