ADME/PK Leader – Genetic Medicines Programs

BioSpace; Boston (MA); On-site; USD 194,000 - 339,000; Full time

Benefits offered by this job

Company bonus

Comprehensive benefits package

401(k) retirement plan

Job summary

Lilly is seeking an experienced ADME/DMPK scientist for our Boston campus to lead ADME studies supporting preclinical and clinical genetic medicines. You will integrate ADME/PKPD data with discovery chemistry and biology to inform design, delivery, and regulatory strategies.

We value strong problem-solving skills, global collaboration, and the ability to communicate complex data to diverse teams. This is a full-time, on-site role in Boston, MA with a competitive benefits package.

Qualifications

• Ph.D. or equivalent in a relevant scientific field with substantial ADME/PKPD experience.
• Strong problem-solving skills and ability to test ADME hypotheses across modalities.
• Experience integrating ADME/PKPD data with discovery biology and chemistry data.

Responsibilities

• Lead ADME studies to support preclinical and clinical development of genetic medicines.
• Integrate ADME, PK and PK/PD endpoints with discovery data to guide design and delivery strategies.
• Design and interpret hypothesis-driven studies addressing TK and toxicokinetics questions.
• Collaborate cross-functionally and with regulatory teams on global submissions.
• Prepare ADME portions of regulatory documents and interact with authorities.
• Mentor colleagues and foster cross-level coaching and collaboration.
• Communicate clearly to influence teams and stakeholders.

Skills

Learning agility

ADME/PKPD knowledge

Data integration across in silico/in_v

Education

PhD in Biochemistry/Biology/Pharmacokinetics/Bioengineering/Pharmacology

5+ years pharma/biotech ADME/PKPD experience

Tools

PK/PD modeling

Bioanalytical methods (LC/MS, PCR)

Job description

Lilly is seeking an experienced ADME/DMPK scientist for our Boston campus to lead ADME studies supporting preclinical and clinical genetic medicines. You will integrate ADME/PKPD data with discovery chemistry and biology to inform design, delivery, and regulatory strategies.

We value strong problem-solving skills, global collaboration, and the ability to communicate complex data to diverse teams. This is a full-time, on-site role in Boston, MA with a competitive benefits package.