12-Hour GMP Manufacturing Tech — Purification

Amgen Inc.; Thousand Oaks (CA); On-site; USD 71,000 - 96,000; Full time

Job summary

Amgen Inc. in Thousand Oaks is seeking an Associate Manufacturing to join a 24/7 production environment at the Drug Substance plant.

You will perform hands-on operations, follow SOPs, and support development, clinical, and commercial launch activities with a focus on purification, chromatography, and aseptic processing. You will monitor processes, assist in documentation reviews, and participate on cross-functional teams.

Qualifications

• Knowledge of large scale purification operations and related processes.
• Familiarity with CFR/regulatory requirements and GMP practices.
• Ability to interpret and apply GMP knowledge to manufacturing tasks.
• Experience with troubleshooting and basic process improvements.

Responsibilities

• Operate in a dynamic production environment per SOPs.
• Set up, clean, sanitize, and prepare media and buffers.
• Monitor critical processes and complete routine validation.
• Draft/revise routine documents such as MPs, SOPs, reports.
• Identify and report quality incidents and potential improvements.

Skills

Purification operations knowledge

Chromatography

TFF (Tangential Flow Filtration)

Aseptic processing

GMP knowledge

Basic troubleshooting

DeltaV / automation

Quality incident initiation

Education

Bachelor’s degree

Associate’s degree + 6 months experience

High school diploma / GED + 2 years experience

Tools

LIMS access

DeltaV automation

Job description

Amgen Inc. in Thousand Oaks is seeking an Associate Manufacturing to join a 24/7 production environment at the Drug Substance plant.

You will perform hands-on operations, follow SOPs, and support development, clinical, and commercial launch activities with a focus on purification, chromatography, and aseptic processing. You will monitor processes, assist in documentation reviews, and participate on cross-functional teams.