Stem Cell Scientist: Kidney Organoids & Genome Editing

A*STAR RESEARCH ENTITIES; Singapore; On-site; SGD 80,000 - 120,000; Full time

Job summary

A*STAR RESEARCH ENTITIES is seeking a Scientist in Human Stem Cell and Kidney Organoid Research to develop hPSC-derived organoid models for kidney development and disease mechanisms. The role spans stem cell biology, genome engineering, imaging, and animal models, with emphasis on multidisciplinary collaboration.

You will advance organoid and assembloid models, optimise protocols, and contribute to publications, while supporting lab management and cross-team training in a dynamic research

Qualifications

• PhD in Biomedical Sciences or a related discipline is required.
• First-author publications in peer-reviewed journals are advantageous.
• Experience in CRISPR-Cas9 genome editing.
• Experience in hPSC culture and 3D organoid culture.
• Experience in microscopy is preferred.
• Experience in mouse models and animal experiments is advantageous.
• Experience in analysing sequencing data is advantageous.

Responsibilities

• Design and execute in vitro and in vivo experiments with hPSC-derived kidney organoids and assembloids.
• Develop and optimize organoid engineering, differentiation, and imaging workflows.
• Perform tissue collection, molecular analyses, and data interpretation.
• Collaborate with PI and team; contribute to manuscripts and grant proposals.
• Train students and junior staff; assist with lab management and safety tasks.
• Contribute to regulatory compliance and maintenance of shared resources.
• Undertake additional research and administrative duties as assigned.

Skills

Stem cell biology

3D organoid culture

Genome editing (CRISPR-Cas9)

Microscopy

Animal experimentation

NGS data analysis

English communication

Education

PhD in Biomedical Sciences or related

Job description

A*STAR RESEARCH ENTITIES is seeking a Scientist in Human Stem Cell and Kidney Organoid Research to develop hPSC-derived organoid models for kidney development and disease mechanisms. The role spans stem cell biology, genome engineering, imaging, and animal models, with emphasis on multidisciplinary collaboration.

You will advance organoid and assembloid models, optimise protocols, and contribute to publications, while supporting lab management and cross-team training in a dynamic research