Senior RNA Analytical Platform Lead

Singular: Building Brilliant Biotechs; Singapore; On-site; SGD 80,000 - 120,000; Full time

Job summary

A biotech-focused organization in Singapore seeks a Scientist / Senior Scientist for RNA Analytical Development. The role involves developing analytical strategies, implementing advanced methods, and supporting RNA therapeutic initiatives. Candidates should possess a PhD in Analytical Chemistry and expertise in LC-MS and related analytical techniques. This full-time position requires a passion for building cutting-edge RNA analytical systems to support discovery and clinical programs.

Qualifications

• Deep experience with LC-MS, HRMS, CE-SDS, and multiscale purification techniques.
• Hands-on experience analyzing modified oligos and ligand-oligo conjugates.
• Ability to develop analytical characterization strategies for RNA raw materials.

Responsibilities

• Develop analytical characterization strategies for RNA raw materials, DS and DP.
• Implement orthogonal analytical workflows (HPLC, LC-MS, CE, UV, qPCR, DLS, TEM).
• Build scalable, phase-appropriate workflows to support discovery → IND programs.
• Develop SOPs, validation plans, and maintain rigorous documentation (LIMS/ELN).

Skills

Analytical Chemistry expertise

LC-MS experience

High-Throughput Method Development

Analytical Strategy Development

Education

PhD in Analytical Chemistry or related discipline

Tools

HPLC

LC-MS

CE

qPCR

Job description

A biotech-focused organization in Singapore seeks a Scientist / Senior Scientist for RNA Analytical Development. The role involves developing analytical strategies, implementing advanced methods, and supporting RNA therapeutic initiatives. Candidates should possess a PhD in Analytical Chemistry and expertise in LC-MS and related analytical techniques. This full-time position requires a passion for building cutting-edge RNA analytical systems to support discovery and clinical programs.