Senior RNA Analytics Scientist, Translational Platform Lead

Singular: Building Brilliant Biotechs; Singapore; On-site; SGD 80,000 - 120,000; Full time

Job summary

A cutting-edge biotechnology organization in Singapore seeks a Scientist/Senior Scientist in RNA Analytical Development. The ideal candidate will develop analytical strategies for RNA materials, implement various analytical methods, and support the transition of novel therapies from discovery to clinic. A PhD in Analytical Chemistry or related field and extensive experience in analytical techniques are required. Join a rapidly scaling team and contribute to innovative RNA platforms.

Qualifications

• PhD in Analytical Chemistry, Pharmaceutical Sciences, or related discipline.
• Deep expertise with LC-MS, HRMS, CE-SDS, and multiscale purification techniques.
• Hands-on experience analysing modified oligos and ligand-oligo conjugates.

Responsibilities

• Develop analytical characterization strategies for RNA raw materials, DS and DP.
• Implement orthogonal analytical workflows (HPLC, LC-MS, CE, UV, qPCR, DLS, TEM).
• Build scalable, phase-appropriate workflows to support discovery → IND programs.
• Develop SOPs, validation plans, and maintain rigorous documentation (LIMS/ELN).

Skills

Analytical Chemistry expertise

Experience with LC-MS

Ability to develop analytical workflows

Hands-on experience analysing modified oligos

Knowledge of multiscale purification techniques

Education

PhD in Analytical Chemistry or related discipline

Tools

HPLC

CE

UV

qPCR

DLS

TEM

Job description

A cutting-edge biotechnology organization in Singapore seeks a Scientist/Senior Scientist in RNA Analytical Development. The ideal candidate will develop analytical strategies for RNA materials, implement various analytical methods, and support the transition of novel therapies from discovery to clinic. A PhD in Analytical Chemistry or related field and extensive experience in analytical techniques are required. Join a rapidly scaling team and contribute to innovative RNA platforms.