Scientist - Proteomics, IMCB

A*STAR - Agency for Science, Technology and Research; Singapore; On-site; SGD 50,000 - 80,000; Full time

Job summary

A*STAR - Agency for Science, Technology and Research in Singapore is looking for a motivated Research Fellow to join an interdisciplinary program in advanced cancer biology. The role involves designing and executing proteomics analyses and biological validations. Ideal candidates will have a PhD in a relevant life sciences field and postdoc experience. This position offers a chance to contribute to cutting-edge cancer research within a collaborative environment.

Qualifications

• PhD required in a relevant life sciences field.
• 2+ years of postdoc experience in related areas is a plus.
• Hands-on experience with advanced proteomics and biological validations.

Responsibilities

• Design, execute, and interpret advanced proteomics analyses.
• Optimize and implement novel proteomics workflows.
• Perform biological and translational validation of findings.
• Train junior researchers and students when needed.

Skills

Advanced MS-based proteomics

Biological validations

Spatial proteomics

Clinical samples handling

Biochemical assays

Imaging techniques

Education

PhD in Biochemistry, Biology, Chemistry, Proteomics or related life sciences field

Job description

Job Description

IMCB’s JG Lab is seeking a highly motivated and talented Research Fellow to join a competitive, interdisciplinary research programme on advanced cancer biology. The successful candidate will play a key role in executing cutting‑edge cancer proteomics analyses, and integrated validation using cell, spatial, and translational biology approaches.

This position offers the opportunity to work at the interface of state‑of‑the‑art proteomics, spatial biology, and clinical translation, within a vibrant, highly collaborative research environment.

Key Responsibilities

• Design, execute, and interpret advanced proteomics analyses (both Mass Spectrometry (MS) and Non-MS), including targeted and untargeted approaches.
• Develop, optimize, and implement novel proteomics workflows/technologies for actionable proteome analysis.
• Perform biological and translational validation of proteomics findings using: Clinical samples, cell culture, organoid, and/or animal models; Biochemical, molecular, and spatial biology assays.
• Conduct imaging- and mechanics‑based validation, including techniques such as SHG, AFM or related modes.
• Contribute to and support assay and prototype development for functional and translational readouts.
• Handle and manage clinical samples, ensuring compliance with regulatory and ethical requirements.
• Prepare scientific reports, presentations, and manuscripts, and contribute to grant‑related activities where appropriate.
• Train junior researchers and students when needed.
• Work closely with the lead PI, collaborating PIs, clinicians, and interdisciplinary teams across proteomics, spatial biology, and cancer research themes.
• Undertake related administrative and project coordination duties as required.

Requirements

• PhD in Biochemistry, Biology, Chemistry, Proteomics or related life sciences field.
• Hands‑on experience in advanced MS‑based proteomics, biological validations and spatial proteomics (plus).
• Experience with clinical samples, biochemical assays and imaging preferred.
• 2+ years of postdoc experience in the related area/s with a track record is a plus.