Research Fellow (OR/CSCB/HJH)

National University of Singapore; Singapore; Hybride; SGD 90 000 - 150 000; Plein temps

Résumé du poste

National University of Singapore's CSCB Programme seeks a lead researcher to drive complex cancer biology studies. You will plan, organize and conduct advanced experiments, while mentoring graduate students and coordinating with the PI.

The role emphasizes leadership, independent project design, and impactful publications. Applicants should have a PhD with 6+ years of relevant experience in NGS, chromatin biology and drug discovery, and demonstrate strong communication and collaboration skills

Qualifications

• PhD in a relevant scientific field with at least 6 years of research experience.
• Strong expertise in next-generation sequencing technologies and cancer chromatin biology.
• Proven experience in drug discovery and screening, including assay development and validation.
• Experience in designing and conducting biochemical, molecular, cellular and cancer dependency assays.
• Experience in in vivo animal studies, including experimental design and pharmacological assessment.
• Strong research leadership, scientific independence and a track record of high-impact publications.
• Excellent analytical, critical thinking, writing, communication and presentation skills.

Responsabilités

• Lead planning, organizing and conducting research activities within the project scope under PI supervision.
• Independently design and execute experimental research required by the project.
• Write and review research papers; present outcomes and develop plans for independent research.
• Support external grant/protocol development and study design.
• Source financial support by investigating funding sources and coordinating with PIs on grant applications.
• Contribute to educational activities and project management; mentor students and research staff.
• Maintain optimal experiment progress and ensure quality and reproducibility.

Connaissances

Next-generation sequencing

Chromatin biology

Drug discovery

Biochemical assays

Molecular biology

In vivo studies

Scientific leadership

Communication skills

Formation

PhD

Description du poste

The Cancer and Stem Cell Biology (CSCB) Programme studies the causes and treatments of cancer and related diseases. The CSCB research groups have diverse programmes in both basic cancer biology and clinical-translational studies, with a special emphasis on cancers that affect the Asian community in general.

The selected candidate will provide leadership and expertise in conducting complex research activities, including but not limited to planning, organising, conducting, and communicating research studies within the overall scope of a research project under the supervision of the Principal Investigator or his/her designate, including but not limited to the following:

• Application of qualitative and quantitative research techniques which include accurate in-depth assessment, interpretation and evaluation of research outcomes, conceptualise new ideas and develop plans forindependent research which could have a considerable influence and impact on the relevant field in attracting research funding.
• Independently carry out the design and execution of experimental research required by the research component of the project.
• Write and review research papers, present research outcomes, conceptualise new ideas and develop plans for independent research which could have a considerable influence and impact on the relevant field attracting research funding.
• Provide support for external grant/protocol development, study design and management of research activities.
• Source financial support for research activities by investigating potential sources of funding, collaborate with Principal Investigators to write and revise grant/fellowship applications.
• Contribute to occasional educational / instructional activities and project management.
• Provide guidance and mentorship to graduate/undergraduate / medical students and research assistants.
• Maintain optimal experiment progress in the laboratory or in the research work undertaken by conducting, supervising, assessing laboratory experiments and outcomes, and to revise and analyse targets to ensure results with good quality and reproducibility.
• Perform other related duties incidental to the work described therein.

Job Requirements

• PhD in a relevant scientific field and/or postdoctoral experience, with at least 6 years of relevant research experience and/or training.
• Strong expertise in next-generation sequencing technologies and their application in tissue and cell-line models.
• Demonstrated expertise in cancer chromatin biology, including chromatin structural aberrations and chromatin-modifying enzymes.
• Proven experience in drug discovery and screening, including assay development, optimisation, compound screening, hit identification and validation, and mechanism-of-action studies.
• Experience in designing and conducting biochemical, molecular, cellular and cancer dependency assays.
• Experience in in vivo animal studies, including experimental design, animal handling, dosing and assessment of pharmacological or biological effects.
• Strong research leadership, scientific independence and a track record of high-impact publications.
• Excellent analytical, critical thinking, writing, communication and presentation skills.
• A team player who is able to prioritise, multi-task and work collaboratively in a diverse workforce.
• Highly motivated and capable of managing and contributing to multiple projects simultaneously.

We regret that only shortlisted candidates will be notified.