Scientist, Neurometabolism & Metabolic Disorders, IMCB

A*STAR RESEARCH ENTITIES; Singapore; On-site; SGD 120,000 - 160,000; Full time

Job summary

A*STAR RESEARCH ENTITIES is seeking a highly motivated Scientist to join a multidisciplinary team in Singapore. The role focuses on developing novel metabolic health strategies, managing end-to-end experimental data, and contributing to grant applications and publications.

The successful candidate will perform cell culture, molecular biology techniques, and in vivo studies, while coordinating with collaborators and PI to advance research projects.

Qualifications

• Ph.D. in Life Science, Biomedical Science or related field with solid publication / preprint record.
• At least 3-5 years of relevant experience in laboratory and animal work.
• Bonus/Advantageous: Prior technical competency in metabolic profiling and/or end-point sampling and tissue collection.
• Excellent critical thinking, interpersonal, written and oral communication skills with a rigorous approach to experimental controls, reproducibility, and data integrity.
• Excellent collaborative mindset with ability to multitask across multiple project streams and work both in teams and independently.
• Highly motivated and willing to learn.

Responsibilities

• In vitro & wet lab experiments: Cell culture, molecular biology and assays (RNA/protein extraction, RT-qPCR, Western blotting, ELISAs), microscopy.
• Routine animal husbandry and colony management: Breeding, weaning, ear-notching/tagging, genotyping and tracking of animal cohorts.
• In vivo handling and experiments: Diet/treatment dosing regimes, body weight & composition analyses, food intake, metabolic phenotyping, blood sampling, glucose/insulin tolerance tests.
• End-point experiments: Terminal blood collection, tissue collection and sample preparation, perfusion, tissue/organ imaging, serum measurements.
• Data Management: Analyze collected data and maintain accurate monitoring and reporting of experimental set-up, protocols, results and research findings.
• Scientific Communication and Research Collaboration: Communicate with PI, collaborators and rest of lab regarding scientific progress and direction, assist in preparation of grant applications, reports, presentation and peer-reviewed journal publications.

Skills

Critical thinking

Interpersonal skills

Communication

Collaboration

Multitasking

Education

Ph.D. in Life Science or related field

Job description

Job Description

We are looking for a qualified individual who is highly motivated, detail-oriented, passionate and committed to laboratory ethics, to be employed for the role of Scientist. The successful candidate will work with a dynamic team on industry projects aiming to develop novel therapeutic strategies towards improving metabolic health. This role offers excellent opportunities to work within a multidisciplinary team and manage end-to-end experimental data packages.

Key Responsibilities

• In vitro & wet lab experiments: Cell culture, molecular biology and assays (e.g. RNA/protein extraction, RT-qPCR, Western blotting, and ELISAs), microscopy etc
• Routine animal husbandry and colony management: Breeding, weaning, ear-notching/tagging, genotyping and tracking of animal cohorts.
• In vivo handling and experiments: Diet/treatment dosing regimes, body weight & composition analyses, food intake, metabolic phenotyping, blood sampling, glucose/insulin tolerance tests etc
• End-point experiments: Terminal blood collection, tissue collection and sample preparation, perfusion, tissue/organ imaging, serum measurements etc
• Data Management: Analyze collected data and maintain accurate monitoring and reporting of experimental set-up, protocols, results and research findings
• Scientific Communication and Research Collaboration: Communicate with PI, collaborators and rest of lab regarding scientific progress and direction, assist in preparation of grant applications, reports, presentation and peer-reviewed journal publications

Qualifications & Requirements

• Ph.D. in Life Science, Biomedical Science or related field with solid publication / preprint record
• At least 3-5 years of relevant experience in laboratory and animal work
• Bonus/Advantageous: Prior technical competency in metabolic profiling and/or end-point sampling and tissue collection
• Excellent critical thinking, interpersonal, written and oral communication skills with a rigorous approach to experimental controls, reproducibility, and data integrity
• Excellent collaborative mindset with ability to multitask across multiple project streams and work both in teams and independently
• Highly motivated and willing to learn