Research Scientist (Mid-Size Molecule Unit)

CHUGAI PHARMABODY RESEARCH PTE. LTD.; Singapore; On-site; SGD 90,000 - 150,000; Full time

Job summary

Chugai Pharmabody Research Pte. Ltd. in Singapore seeks a Research Scientist in the Mid-size Molecule Unit.

The candidate will lead mid-size molecule projects to identify drug candidates and collaborate with cross-disciplinary teams to deliver innovative drug discovery efforts. Applicants should hold a Ph.D. in Biomedical Science or related field with 3 years of relevant experience, and demonstrate expertise in protein engineering, biochemistry, and expression/purification.

Qualifications

• Ph.D. in Biomedical Science/Biochemistry/Chemical Biology/Biotechnology/Information science and 3 years of related experience.

Responsibilities

• Lead mid-size molecule projects through identification of drug candidates.
• Collaborate with cross-functional multi-disciplinary teams to advance drug discovery and technology development.
• Drive integration of chemistry and biotechnology in project efforts.

Skills

Structural biology

Molecular biology

Protein engineering

Antibody engineering

Protein biochemistry

Protein expression

Protein purification

Cross-functional collaboration

High-throughput systems

Automation

Scripting language

Cell biology

Biophysics

Immunology

Education

Ph.D. in Biomedical Science/Biochemistry/Chemical Biology/Biotechnology/Information science

Job description

Chugai Pharmabody Research Pte. Ltd. (“CPR”) was established in Singapore as a wholly-owned subsidiary of Chugai Pharmaceutical Co., Ltd (Chugai), a member of Roche group, in January 2012 and started operations on July 2, 2012. Located at Geneo in Singapore, it aims to generate new antibody drugs based on Chugai’s proprietary antibody engineering technologies, such as recycling antibody®, sweeping antibody®, bispecific antibody, various Fc engineered antibodies, cyclic peptides and other new antibody engineering technologies that are under development.

Position – Research Scientist in Mid-size Molecule Unit

CPR is seeking for a scientist with expertise in protein engineering. You will leverage your passion and creativity to lead mid-size molecule projects through the identification of drug candidates, collaborating with other multi-disciplinary teams to achieve a milestone of a project. The candidate will play a key role to drive our innovative drug discovery projects and cutting-edge technology development through the fusion of chemistry and biotechnology.

Job requirements

The applicant should be highly skilled in at least one of the following areas:

• Strong and proven expertise in structural biology, molecular biology, and chemical biology for protein structure/function investigation.
• Advance knowledge in protein, peptide, and/or antibody engineering, including but not limited to rational or random mutagenesis engineering approach.
• Expertise in protein biochemistry, protein expression, purification, and characterization.
• Strong organizational skills to deal with large amounts of data and excellent communication and collaborative skills, as well as a team player mindset for working with cross-functional multi-disciplinary teams.
• Knowledge and skill of high-throughput system, automation, and/or general scripting language is a plus but not a must.
• Knowledge and skill of cell biology, biophysics or immunology is a plus but not a must.

The applicant must have completed and be awarded with a relevant Ph.D. degree in Biomedical Science/Biochemistry/Chemical Biology/Biotechnology/Information science with 3 years of working experience in a related field. In addition, the successful candidates must be able to demonstrate technical expertise in areas which may include molecular biology, cell biology, protein chemistry and protein engineering as evidenced by projects, presentations, or peer-reviewed scientific publications.

As frequent communication and liaison is expected between both the Singapore and Japan office, you should possess an excellent command of both spoken and written Japanese and English languages.

For more information regarding our Company, you may refer to our website at:

http://chugai-pharmabody.com/

We regret that only short-listed candidates will be notified