Research Assistant - Translational Pharmacology Unit (TP)

Chugai Pharmabody Research Pte. Ltd.; Singapore; On-site; SGD 36,000 - 52,000; Full time

Job summary

Chugai Pharmabody Research Pte. Ltd. is seeking a motivated Research Assistant to join the Translational Pharmacology Unit in Singapore.

You will support in vivo and in vitro pharmacology studies, establish and characterise pharmacology models, and evaluate drug efficacy and biological activity. The role involves PK/PD studies, biomarker assessments, and collaboration across teams. You will work with SOPs, ensure data quality, and assist with animal studies while developing your technical skills

Qualifications

• Degree in Biomedical Science/Biochemistry/Chemical Biology/Biotechnology/Molecular Biotechnology or related field.
• Hands-on experience with one or more of the following techniques: Molecular Biology, Cell Culture, Flow Cytometry, qPCR.
• Familiarity with basic laboratory procedures and data recording.
• Candidates with experience in handling animals such as mice, rats and/or rabbits are encouraged to apply.

Responsibilities

• Support evaluation of drug efficacy, pharmacological activity and biological activity.
• Establish and maintain in vivo pharmacology models to support drug discovery and development.
• Perform PK/PD and biomarker studies for translational research.
• Follow SOPs and ensure procedures are performed safely and consistently.
• Carry out animal husbandry duties and routine study maintenance.

Skills

Molecular Biology

Cell Culture

Flow Cytometry

qPCR

Animal handling

Education

Bi Biomedical/Biochemistry/biotech related degree

Job description

Chugai Pharmabody Research Pte. Ltd. (“CPR”) was established in Singapore as a wholly-owned subsidiary of Chugai Pharmaceutical Co., Ltd (Chugai), a member of Roche group, in January 2012 and started operations on July 2, 2012. Located at Geneo in Singapore, it aims to generate new antibody drugs based on Chugai’s proprietary antibody engineering technologies, such as recycling antibody®, sweeping antibody®, bispecific antibody, various Fc engineered antibodies, and other new antibody engineering technologies that are under development.

Research Assistant – Translational Pharmacology Unit

Overview

We are seeking a motivated Research Assistant to join our Translational Pharmacology Unit. In this role, you will support the unit through in vivo and in vitro pharmacology studies, including the establishment and characterisation of in vivo pharmacology models, evaluation of drug efficacy and biological activity, assessment of mechanism of action, and support of PK/PD and biomarker studies for therapeutic candidates.

You will work according to established SOPs, ensure high standards of data quality and integrity, and participate in routine laboratory maintenance and animal husbandry duties. You will also collaborate closely with team members and colleagues from other units.

You communicate clearly, collaborate well in multidisciplinary settings, and take ownership of assigned tasks. You are eager to learn, open to feedback, and committed to continuously improving your technical skills. You work with care and attention to detail, stay organized, and manage multiple tasks in a fast-paced environment.

Key Responsibilities:

• Support the evaluation of drug efficacy, pharmacological activity and biological activity.
• Establish, maintain and characterise in vivo pharmacology models to support drug discovery and development projects.
• Perform Pharmacokinetic (PK), Pharmacodynamic (PD), and biomarker studies to support translational research.
• Follow experimental protocols carefully and ensure all procedures are performed consistently, safely, and in compliance with SOPs.
• Carry out animal immunization procedures and monitor study outcomes according to established protocols.
• Perform animal husbandry duties, including animal care, health monitoring, record maintenance and related activities in accordance with established protocols.

Requirements

• Degree in Biomedical Science/Biochemistry/Chemical Biology/Biotechnology/Molecular Biotechnology or related field.
• 0-2 years of relevant research experience. Fresh graduates with a keen interest in in vivo pharmacology are welcome to apply.

• Familiarity with basic laboratory procedures, including sample preparation, pipetting, reagent preparation, and data recording.
• Hands-on experience with one or more of the following techniques is preferred:
  • Molecular Biology techniques
  • Cell Culture
  • Flow Cytometry
  • Quantitative Polymerase Chain Reaction (qPCR)
• Candidates with experience in handling animals such as mice, rats and/or rabbits are highly encouraged to apply.

For more information regarding our Company, you may refer to our website at:
http://chugai-pharmabody.com/

We regret that only short-listed candidates will be notified