Director of Therapeutic Antibody Discovery & Engineering

hengrui pharma; Singapore; On-site; SGD 320,000 - 540,000; Full time

Benefits offered by this job

Competitive salary

Career development

Job summary

Hengrui Pharma in Singapore is seeking a Director of Therapeutic Antibody Discovery to lead antibody discovery programs from target discovery through preclinical development. You will oversee antibody generation, engineering, and optimization, and provide scientific leadership across teams.

The role involves managing CROs and academic collaborations, guiding in vitro and in vivo studies, and ensuring regulatory readiness while advancing novel therapeutic antibodies such as monoclonal and

Qualifications

• Ph.D. in immunology, molecular biology, biochemistry, or related field focusing on antibody biology or therapeutic antibodies.

Responsibilities

• Lead antibody drug discovery team and oversee generation, engineering, and optimization.
• Manage cross-functional teams to advance programs from target validation to candidate selection.
• Oversee in vitro and in vivo studies to assess efficacy, PK, safety, and manufacturability.
• Foster collaborations with CROs, academia, and industry partners.
• Ensure regulatory compliance and contribute to publications and filings.

Skills

Leadership

Cross-functional leadership

Antibody biology

Project management

Communication

Problem solving

Education

PhD in immunology or related field

Tools

Phage display

Hybridoma

NGS-based approaches

Transgenic animal platforms

Job description

Hengrui Pharma in Singapore is seeking a Director of Therapeutic Antibody Discovery to lead antibody discovery programs from target discovery through preclinical development. You will oversee antibody generation, engineering, and optimization, and provide scientific leadership across teams.

The role involves managing CROs and academic collaborations, guiding in vitro and in vivo studies, and ensuring regulatory readiness while advancing novel therapeutic antibodies such as monoclonal and