Developing Bioprocesses for Enzyme Production
Allozymes Pte Ltd
Life Science Researcher
BioTech
Bachelor’s
No. of vacancies: 1
Project Description
Role Summary
The Bioprocess Development apprentice will support bioprocess development activities, gaining hands-on experience in media preparation, fermenter maintenance, process monitoring, sample preparation, and analytical instrument operation. This apprenticeship provides an opportunity to learn and apply aseptic techniques and laboratory procedures in a real-world setting. The intern will work collaboratively with the team, contributing to the efficient execution of experiments and supporting bioprocess development projects.
Responsibilities
- Media and Buffer Preparation:
- Assist in the preparation and formulation of media and buffer solutions following established protocols.
- Learn and practice proper autoclaving procedures to ensure media sterility.
- Fermenter Operation and Maintenance:
- Assist in cleaning-in-Place (CIP) procedures for fermenters.
- Help prepare and set up fermenters for experimental runs, ensuring readiness for use.
- Assist in the calibration and maintenance of pH and Dissolved Oxygen (DO) probes.
- Participating in autoclaving fermenters and related equipment as required.
- Fermentation Process Monitoring and Control:
- Assist in monitoring and controlling fermentation processes according to Standard Operating Procedures (SOPs).
- Learn to collect and record data accurately and consistently.
- Sample Preparation and Analysis:
- Assist in preparing fermentation samples for downstream analysis.
- Learn to operate and maintain Gas Chromatography (GC) and High-Performance Liquid Chromatography (HPLC) systems for sample analysis.
- Laboratory Equipment Operation and Maintenance:
- Learn to operate and maintain various laboratory equipment, including pH meters, spectrophotometers, analytical balances, centrifuges, microscopes, biosafety cabinets (BSCs), autoclaves, and hot air ovens, according to SOPs.
- Data Management and Documentation:
- Assist in maintaining accurate and detailed laboratory records of experimental data.
- Learn to document all procedures and results in accordance with good documentation practices.
- Scientific Research and Literature Review:
- Assist in online searches and review scientific literature to support experimental design and process development.
- Laboratory Safety and Compliance:
- Adhere to all laboratory safety protocols and procedures.
- Participate in the implementation and maintenance of laboratory safety measures.
- Collaboration and Communication:
- Collaborate effectively with team members to achieve project goals.
- Communicate clearly and effectively with colleagues and supervisors.
- Be flexible to work shifts as required.
- Adapt to evolving bioprocess needs.
Qualifications
- Currently pursuing a Bachelor’s degree in Biotechnology, Microbiology, Chemical Engineering, or a related field; or Diploma with relevant experience
- Basic understanding of aseptic techniques and laboratory procedures.
- Interest in fermenter operation and maintenance.
- Eagerness to learn and operate analytical instruments such as GC and HPLC.
- Good documentation and record-keeping skills.
- Strong attention to detail and ability to follow SOPs.
- Ability to work effectively in a team environment.
- Good communication and interpersonal skills.
- Ability to work shifts when required.
- Ability to follow strict safety protocols.
Minimum duration of the project
6 months
Required Skills
- Bioprocessing Skills
- Biology