Clinical Laboratory Technician

Fundação Champalimaud; Lisboa; Híbrido; EUR 42 000 - 68 000; Tempo integral

Resumo da oferta

Fundação Champalimaud, based at Champalimaud Centre for the Unknown in Lisbon, Portugal, seeks a Technical professional to advance GMP production of cell therapies and immune-monitoring. The role emphasizes collaboration with international partners and clinical colleagues in immunotherapy programs.

We expect strong expertise in immunology, cellular analysis, flow cytometry, and tissue culture, with the ability to travel for international projects and maintain rigorous QC documentation.

Qualificações

• Strong knowledge in human T-/B-cell biology and immunology.
• Practical and theoretical knowledge in cellular analysis and immunological assays to gauge cellular and humoral immune responses.
• Experience with LV and non-LV gene transfer is a plus.
• Skills in DNA and RNA processing.
• Strong expertise in molecular technologies, flow cytometry, T-cell sorting, and immune effector functions.
• Willingness to travel for clinical, international projects.
• Fluency in English (written and spoken).

Responsabilidades

• Lab management and organisation with an excellent team and collaborative spirit within the institution and with international partners.
• Close interaction with clinical colleagues and within immunotherapeutic programs.
• Analysis and interpretation of immune responses.
• Procurement of clinical samples and processing for molecular and functional analysis.
• Procurement of cellular products for therapy (vector and non-vector).
• Expertise in tissue culture.
• Advanced flow cytometric analyses.
• Commitment to QC documentation and traceability.

Conhecimentos

T-/B-cell biology

Immunoassays

LV gene transfer

DNA/RNA processing

Molecular technologies

Flow cytometry

T-cell sorting

Travel for international projects

English fluency

Formação académica

Master's degree

Descrição da oferta de emprego

Location: Champalimaud Centre for The Unknown

Job Type: Full Time

Position: Technical

Application Starts: 24 Sep. 2025

The Cell Centre is looking to expand efforts in the GMP production of cell products with a specific focus on immune-monitoring.

The successful applicant is expected to be pivotal co-worker in the development and improvement of immune cell-based therapies for malignant diseases and the preparation of GMP compliant production of cellular products including gene-modified immune cells and monitoring of anti-cancer directed vaccination.

Duties & Responsibilities

• Lab management and organisation with an excellent team and collaborative spirit within the institution and with our international partners;
• Close interaction with clinical colleagues and within immunotherapeutic programs;
• Analysis and interpretation of immune responses;
• Procurement of clinical samples and subsequent processing for molecular and functional analysis;
• Procurement of cellular products for (non-vector and vector-based) therapy;
• Excellent expertise in in tissue culture;
• Advanced flow cytometric analyses;
• Excellent knowledge or dedication to acquire strong skills in QC documentation.

Qualifications & Skills

• Strong knowledge in human T-cell and B-cell biology and immunology;
• Documented and well advanced practical and theoretical knowledge in cellular analysis and immunological assays to gauge cellular and humoral immune responses;
• Previous work experience with lentiviral (LV) and non-LV based gene transfer is a plus;
• Skills in DNA and RNA processing;
• Very good knowledge in molecular technologies, excellent knowledge in flow cytometry, T-cell sorting and gauging immune effector functions;
• Team spirit and will to collaborate within the foundation and with our partner institutions with the possibility to travel for clinical, international projects;
• Fluency in English and excellent communication skills (written and verbal) in English.

Requirements

• Research Field: Biological sciences » Other
• Education Level: Master Degree or equivalent

About Us

Research is at the heart of the Champalimaud Centre for the Unknown, a modern research and clinical facility situated on the waterfront in Lisbon, Portugal. Champalimaud Research comprises a team of over 250 scientists from around the world with foci in neuroscience and cancer research with a strong development in the production of cell therapy products. English is the official language of the Centre. Lisbon’s sunny Atlantic-Mediterranean climate, vibrant culture and high quality of life make this a great place to live and work.