Postdoc: Biophysics-Aware ML for Multi-Omics Cancer Genomics

Twoja Norwegia; Lørenskog; Remote; NOK 595,000 - 679,000; Full time

Benefits offered by this job

Good welfare schemes

Exercise up to 1.5 hours/week

Public sector pension (Statens Pensjon

Job summary

University of Oslo (UiO) invites applications for a Postdoctoral Research Fellow in Bioinformatics and Computational Biology at the EpiGen unit, Campus Ahus, Lørenskog. The three-year fellowship emphasizes developing a biophysically interpretable ML framework that unifies TF-DNA interactions, epigenetic features and 3D genome data to identify functional long-range gene regulatory interactions in cancer.

The successful candidate will collaborate with molecular biologists, bioinformaticians and

Qualifications

• PhD required in bioinformatics/computational biology or related field
• Demonstrated English proficiency (written and spoken)
• Doctoral degree submitted by deadline with public defense eligibility
• Strong personal suitability and motivation for the project
• Knowledge of statistics, data mining, and machine learning methods
• Skills in shell scripting, R, Python, and C programming
• Experience in big data analysis and computational tool/package development
• Experience in HTS data analysis or computational genome regulation

Responsibilities

• Develop a biophysically interpretable machine learning framework integrating TF-DNA interactions, epigenetic features and 3D genome data
• Integrate multi-omics data from single-cell experiments to improve predictive accuracy and interpretability
• Validate predictions on cancer genomes and collaborate with multidisciplinary teams
• Publish high-quality scientific results and contribute to open-source software and bioinformatics tools
• Engage in teaching/supervision and participate in international collaborations and research visits

Skills

Molecular biology

Genomics

Bioinformatics

Machine learning

Data mining

Computational programming

Shell scripting

R

Python

C programming

Education

PhD in bioinformatics/computational biology

PhD in related quantitative fields (CS/Physics/Math)

Tools

R

Python

C programming

Shell scripting

Big data analysis tools

Hi-C analysis tools

Job description

University of Oslo (UiO) invites applications for a Postdoctoral Research Fellow in Bioinformatics and Computational Biology at the EpiGen unit, Campus Ahus, Lørenskog. The three-year fellowship emphasizes developing a biophysically interpretable ML framework that unifies TF-DNA interactions, epigenetic features and 3D genome data to identify functional long-range gene regulatory interactions in cancer.

The successful candidate will collaborate with molecular biologists, bioinformaticians and