Postdoc: Medicinal Chemistry for Piezo1 Inhibitors

Utrecht University - Faculty of Science; Utrecht; On-site; EUR 41,000 - 64,000; Full time

Job summary

Utrecht University - Faculty of Science in Utrecht, Netherlands, invites applications for a postdoctoral position in Medicinal Chemistry. The role focuses on discovering and developing Piezo1 inhibitors for sickle cell disease, combining virtual screening, AI techniques and organic synthesis.

You will work with UMC Utrecht, access modern labs, and contribute to translational efforts while expanding expertise in synthetic and computational medicinal chemistry.

Qualifications

• PhD in Medicinal Chemistry completed.
• Experience in organic synthesis of drug-like compounds.
• Experience in molecular modelling and docking to create bioactive compounds.
• Excellent written and spoken English.

Responsibilities

• Conduct discovery and development of novel Piezo1 inhibitors for sickle cell disease.
• Utilize virtual screening, AI techniques and organic synthesis to optimize inhibitors.
• Collaborate with researchers at UMC Utrecht and support translational activities.

Skills

PhD in Medicinal Chemistry

Organic synthesis of drug-like

Molecular modelling/docking

Proficiency in English

Education

PhD in Medicinal Chemistry

Job description

Utrecht University - Faculty of Science in Utrecht, Netherlands, invites applications for a postdoctoral position in Medicinal Chemistry. The role focuses on discovering and developing Piezo1 inhibitors for sickle cell disease, combining virtual screening, AI techniques and organic synthesis.

You will work with UMC Utrecht, access modern labs, and contribute to translational efforts while expanding expertise in synthetic and computational medicinal chemistry.