PhD in HIV-Driven Neurodegeneration & Brain Organoids

Amsterdam UMC

Amsterdam

On-site

EUR 36,000 - 45,000

Full time

44 hours ago
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Benefits offered by this job

Public transport reimbursement
Bike scheme
Secondments abroad
Biosecurity training
MBA prep program
Conferences & PD plan
End-of-year bonus 8.3%

Job summary

Amsterdam UMC in Amsterdam is launching a PhD position under the MERIT MSCA network to study HIV-induced neurodegeneration using iPSC-derived brain organoids. You will explore lipidomic changes and TDP-43 proteinopathy within organoids, contributing to Work Packages 1 and 2 under senior supervision.

The role requires a motivated candidate with strong biology background, English proficiency, and willingness to mobility constraints.

Qualifications

  • MSc or MD in (bio)medical sciences, biology, cell biology, biotechnology or closely related field
  • Strong foundation in molecular and cellular biology and immunology
  • Experience in virology, (3D) cell culture, or tissue engineering
  • Excellent English communication (CEFR C1/C2)
  • Transnational mobility rule: have not resided/carried out work in the NL for more than 12 months in the past 36 months
  • Experience with experimental lab techniques; analytical and problem-solving skills; ability to work in multidisciplinary team

Responsibilities

  • Characterise lipidomic profiles of HIV-infected brain organoids vs healthy controls
  • Assess and alter TDP-43 proteinopathy in HIV-infected organoids
  • Contribute to Work Packages 1 and 2 under supervision
  • Collaborate with OrganoVIR Labs teams at Amsterdam UMC

Skills

Virology
3D cell culture
Tissue engineering
Molecular & cellular biology
Immunology
Analytical thinking
Independent & collaborative work
English proficiency

Education

MSc or MD in biomedical sciences / biology
Near completion of MSc or MD

Tools

Organoid culture
Cell culture techniques
Microscopy

Job description

Amsterdam UMC in Amsterdam is launching a PhD position under the MERIT MSCA network to study HIV-induced neurodegeneration using iPSC-derived brain organoids. You will explore lipidomic changes and TDP-43 proteinopathy within organoids, contributing to Work Packages 1 and 2 under senior supervision.

The role requires a motivated candidate with strong biology background, English proficiency, and willingness to mobility constraints.

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