PhD in Cellular Neuroscience: Synapse & mRNA Dynamics

Vrije Universiteit; Amsterdam; Hybrid; EUR 38,000 - 49,000; Full time

Benefits offered by this job

ABP pension

8% holiday allowance

8.3% end-of-year bonus

Commuting expenses contribution

Sport facilities on site

38-hour full-time week

Job summary

Vrije Universiteit Amsterdam is offering a PhD position in the Functional Genomics department to investigate how synaptic mRNA capture and translation regulate synapse formation, using rodent neurons and human iPSC-derived neurons.

You will use and develop genetic and imaging tools, perform live-cell and super-resolution imaging, publish analyses in peer-reviewed journals, and contribute to teaching activities as part of an international research network.

Qualifications

• Masters degree in life sciences, biomedical sciences or biophysics with neuroscience specialization.
• Hands-on experience with molecular and cellular neuroscience.
• Hands-on imaging experience is an advantage.
• Fluent in English (written and spoken) with good communication skills.

Responsibilities

• Imaging of mRNA, translation and receptors at synaptic sites in cultured rodent and human iPSC-derived neurons.
• Investigate and control dynamics of mRNAs and ribosomes by developing novel genetic and imaging tools with live-cell and super-resolution imaging.
• Perform functional assays to study synapse formation and function.
• Publish analyses in peer-reviewed journals and provide progress reports to funding sources.
• Contribute to teaching activities (approx. 10%), including supervision of BSc and MSc students during internships.
• Present your work to the international research community.

Skills

Molecular neuroscience

Cellular neuroscience

Imaging proficiency

English communication

Education

Master degree in life sciences / biomedical sciences / biophysics with neuroscience specialization

Tools

Live-cell imaging

Super-resolution imaging

Job description

Vrije Universiteit Amsterdam is offering a PhD position in the Functional Genomics department to investigate how synaptic mRNA capture and translation regulate synapse formation, using rodent neurons and human iPSC-derived neurons.

You will use and develop genetic and imaging tools, perform live-cell and super-resolution imaging, publish analyses in peer-reviewed journals, and contribute to teaching activities as part of an international research network.