Head of Antibody Discovery & Innovation

VectorY Therapeutics; Amsterdam; Hybride; EUR 90 000 - 160 000; Plein temps

Résumé du poste

VectorY Therapeutics is seeking a Principal Scientist, Head of Antibody Discovery to lead and shape our antibody and intrabody discovery efforts. You will drive scientific strategy, mentor a high-performing team, and advance innovative antibody-based therapeutics for neurodegenerative diseases.

As part of the Discovery team, you will define antibody discovery strategies across programs, ensuring rigor, timely delivery of candidates, and integration of AI-guided approaches with cutting-edge

Qualifications

• PhD required in immunology, molecular biology, biochemistry, or related field.
• 10+ years of antibody discovery and engineering experience (biotech/pharma preferred).
• Protein/antibody engineering essential; structural biology and computational design strongly preferred.
• Proven track record of delivering antibody candidates from discovery to development.
• Deep expertise in discovery platforms (Phage/yeast/mammalian display, B cell screening, single-cell technologies).
• Demonstrated experience in leading teams and managing complex programs.
• Excellent communication skills in English.

Responsabilités

• Define and drive the antibody/intrabody discovery strategy aligned with company pipeline goals.
• Lead target-to-lead activities including hit identification, screening, and optimization.
• Establish and continuously improve discovery platforms (display technologies, screening assays, intracellular antibody approaches).
• Integrate advanced technologies (AI-guided design, high-throughput screening, single-cell approaches).
• Provide scientific oversight across multiple preclinical programs.
• Drive data-driven decision-making and ensure high scientific rigor.
• Build, lead, and mentor a multidisciplinary antibody discovery team.
• Foster a culture of innovation, accountability, and collaboration.
• Set clear priorities, goals, and performance expectations.
• Attract, develop, and retain top scientific talent.
• Drive external collaborations (CROs, academic partners, technology providers).
• Continuously evaluate emerging technologies to maintain competitive advantage.
• Contribute to external scientific visibility (publications, conferences, partnerships).
• Support business development activities and due diligence efforts.

Connaissances

Leadership

Strategic thinking

Communication

Data-driven decision making

Stakeholder management

Formation

PhD in Immunology, Molecular Biology, Biochemistry, or related field

Outils

Phage display

Yeast display

Mammalian display

Single-cell technologies

Description du poste

VectorY Therapeutics is seeking a Principal Scientist, Head of Antibody Discovery to lead and shape our antibody and intrabody discovery efforts. You will drive scientific strategy, mentor a high-performing team, and advance innovative antibody-based therapeutics for neurodegenerative diseases.

As part of the Discovery team, you will define antibody discovery strategies across programs, ensuring rigor, timely delivery of candidates, and integration of AI-guided approaches with cutting-edge