Director Technical Operations

Prothya Biosolutions Belgium BV; Amsterdam; Hybrid; EUR 180,000 - 260,000; Full time

Job summary

Prothya Biosolutions in Amsterdam seeks a Director of Technical Operations to lead engineering, maintenance, automation, validation, facilities and asset lifecycle with end-to-end accountability. This build-and-transform role focuses on modernizing infrastructure, strengthening governance, and enabling growth in a highly regulated environment.

You will translate strategy into a multi-year roadmap, develop a resilient organization, and partner with Quality, Finance and executive teams to ensure

Qualifications

• Master’s degree in engineering or related field.

Responsibilities

• Define multi-year Technical Operations roadmap covering Engineering, Validation, Automation, Maintenance and Facilities.
• Establish governance and clear prioritization across disciplines to align with growth.
• Lead asset lifecycle and infrastructure modernization with CapEx prioritization.
• Ensure high production uptime through preventive maintenance and lifecycle management.
• Oversee GMP compliance, validation strategies, change control, and audit readiness.
• Lead managers across Technical Operations and build a resilient, change-ready team.
• Ensure health, safety and environmental standards are embedded in daily operations.

Job description

Prothya Biosolutions is at a pivotal moment in its development. As part of Intas Pharmaceuticals, the company is backed by strong long-term investment and a clear ambition to grow into a truly global player in plasma-derived medicines. This ambition is reflected not only in scale, but in the modernization of production infrastructure, the professionalization of technical governance, and the strengthening of operational resilience across our sites. To support this next phase, we are seeking a Director Technical Operations: a senior technical leader who can translate strategic ambition into reliable, compliant, and future-proof operations. This role carries end-to-end accountability for engineering, maintenance, automation, validation, facilities, utilities, and asset lifecycle management, ensuring uninterrupted production while enabling growth. This is a build-and-transform role, not a caretaker position. The Director Technical Operations will define and execute a multi-year technical strategy, modernize infrastructure and systems, strengthen governance, and build a resilient organization capable of supporting both current operations and future expansion in a highly regulated environment.

Location:Amsterdam
Reporting to:SVP Operations
Employment type:Full-time

For the right leader, this role offers:

The opportunity to shape technical direction at enterprise level

A highly visible position where technical strategy directly underpins business continuity and growth

An organization with genuine momentum, long-term commitment, and the mandate to invest and improve

Your key responsibilities

Strategic Technical Leadership & Governance

• Define and translate the Operations strategy into a multi-year Technical Operations roadmap coveringEngineering, Validation, Automation, Maintenance, Utilities, Asset Management, and Facilities
• Establish strong technical governance, decision-making frameworks, and clear prioritization across disciplines
• Ensure alignment with business growth ambitions, quality standards, and regulatory requirements

Asset Lifecycle & Infrastructure Strategy

• Develop and execute a realistic, phased asset lifecycle and infrastructure modernization strategy
• Set CapEx priorities based on compliance, risk, operational impact, and financial feasibility
• Lead long-term planning for buildings, utilities, installations, and critical technical systems

Operational Reliability & Technical Performance

• Define and oversee technical reliability standards to ensure high production uptime
• Ensure effective preventive maintenance, lifecycle management, and escalation processes
• Monitor technical risks, incidents, and performance, ensuring timely corrective and preventive actions

Quality, GMP & Compliance Oversight

• Ensure all technical activities comply withGMP, validation frameworks, and quality systems
• Provide governance on validation strategies, technical change control, and audit readiness
• Proactively identify and mitigate technical and compliance risks in close collaboration with Quality
• Own and manage Technical Operations budgets and CapEx portfolios
• Oversee contract management and strategic supplier partnerships
• Ensure cost control, transparency, and value creation in outsourced technical activities

Leadership & Organizational Development

• Lead, coach, and develop managers across Technical Operations
• Build a resilient organization with clear roles, responsibilities, and spans of control
• Drive engagement, readiness for change, and continuous improvement

Stakeholder Management

• Act as senior technical counterpart for Operations leadership, Quality, Finance, and Executive Management
• Represent Technical Operations in strategic internal and external forums
• Identify and elevate technical, organizational, and compliance risks impacting business objectives

EHS Responsibility

• Ensure health, safety, and environmental standards are embedded in procedures and daily operations
• Promote a strong safety culture with well-informed and accountable teams

Your profile

Education & experience

• Master’s degree (MSc or equivalent) in Engineering, Process Technology, Mechanical, Electrical Engineering, or a related technical field
• 10–15 years’ experiencein pharmaceutical or similarly regulated manufacturing environments
• Deep expertise in technical operations, engineering disciplines, and regulated production environments
• Strong knowledge of GMP, quality systems, validation, and regulatory compliance
• Proven experience with asset lifecycle management, utilities, infrastructure, and maintenance strategies
• Solid understanding of CapEx governance, budgeting, and supplier management
• Strategic and systems thinker with the ability to translate vision into execution
• Strong governance and decision-making capabilities
• Inspirational people leader with experience leading managers
• Excellent stakeholder management at senior and executive level
• Change leader with a pragmatic, risk-based mindset
• Business-oriented, balancing technical excellence, compliance, and financial feasibility

You will play a pivotal role in strengthening and future-proofing critical operations in a highly regulated environment, with real impact on patient safety, business continuity, and long-term growth.