Clinical Trial Delivery Lead - 6-Month Contract

Sire Search; Utrecht; On-site; EUR 70,000 - 100,000; Full time

Job summary

Sire Search is seeking a Clinical Trial Manager to own the operational delivery of clinical trials, lead a cross‑functional trial team, and manage CRO partnerships in a highly regulated life sciences environment.

You will drive trial delivery on time and within budget, oversee budgets, forecasting, accruals and invoicing, monitor CRO performance, and escalate risks to protect progress and data integrity. Strong ICH‑GCP knowledge and SOP adherence are essential.

Qualifications

• Bachelor’s degree in a relevant field; Master’s degree preferred.
• 5+ years of experience in Clinical Operations.
• Proven experience leading and managing clinical trials.
• Strong experience working with CROs and coordinating trial activities.
• Solid understanding of regulated clinical trial delivery and quality expectations (ICH-GCP and SOPs).
• Comfortable working with trial documentation and budget monitoring.

Responsibilities

• Lead the trial-specific cross-functional Clinical Management Team, including oversight of CRO partners.
• Drive trial delivery to meet agreed timelines, budget, and quality expectations.
• Build strong collaboration with internal and external stakeholders to support smooth trial progress.
• Support selection of CROs and contribute to defining scope of work and expectations.
• Actively manage CRO performance and ensure clear communication and follow-up.
• Identify and escalate issues/risks to protect progress and quality.
• Support audits and inspections and drive timely responses.
• Maintain and manage trial budgets, including forecasting, accruals, and invoicing.
• Lead risk management activities related to patient safety and data integrity.

Skills

Leadership

Trial management

CRO coordination

ICH-GCPs

Education

Bachelor's degree

Master’s degree preferred

Job description

Sire Search is seeking a Clinical Trial Manager to own the operational delivery of clinical trials, lead a cross‑functional trial team, and manage CRO partnerships in a highly regulated life sciences environment.

You will drive trial delivery on time and within budget, oversee budgets, forecasting, accruals and invoicing, monitor CRO performance, and escalate risks to protect progress and data integrity. Strong ICH‑GCP knowledge and SOP adherence are essential.