Technician / Senior Technician in Gene Editing - National Facility for Genome Engineering and D[...]

Human Technopole; Milano; In loco; EUR 35.000 - 41.000; Tempo pieno

Descrizione del lavoro

A leading interdisciplinary life science research institute in Milan seeks a Technician / Senior Technician in Gene Editing. The successful candidate will implement and optimize genome engineering pipelines, contributing significantly to patient-specific disease modeling. This role demands a strong background in molecular biology and gene editing technologies, with opportunities for innovative research and collaboration in an esteemed scientific environment.

Servizi

Work-life balance provisions

Italian language training for foreigners

Maternity leave up to 1 year and support for new parents

Possibility of flexible working hours

Support for relocation

Tax benefits where applicable

Competenze

• Master’s degree in a related life science discipline.
• At least 3 years of hands-on experience in molecular biology.
• Proficiency in CRISPR and molecular biology techniques.

Mansioni

• Establish and standardize gene editing technologies.
• Design and execute genome engineering experiments.
• Develop and refine innovative genome engineering strategies.

Conoscenze

CRISPR / Cas genome editing

Molecular biology techniques

Mammalian cell culture

Problem-solving attitude

Interpersonal skills

Formazione

Master’s degree in Molecular Biology

PhD in Molecular Biology (preferred)

Descrizione del lavoro

Technician / Senior Technician in Gene Editing - National Facility for Genome Engineering and Disease Modeling

Join to apply for the Technician / Senior Technician in Gene Editing - National Facility for Genome Engineering and Disease Modeling role at Human Technopole

Technician / Senior Technician in Gene Editing - National Facility for Genome Engineering and Disease Modeling

1 week ago Be among the first 25 applicants

Join to apply for the Technician / Senior Technician in Gene Editing - National Facility for Genome Engineering and Disease Modeling role at Human Technopole

Get AI-powered advice on this job and more exclusive features.

Human Technopole (HT) is a new interdisciplinary life science research institute, created and supported by the Italian government, with the aim of developing innovative strategies to improve human health. HT has the mission of conducting cutting-edge research and to translate innovation into methods and tools available to the entire National scientific community. To this end, HT is opening National Facilities that will provide world-class research infrastructure in the areas of Structural Biology, Light Imaging Microscopy, Genomics, Genome Engineering, and Data Handling and Analysis, aimed at boosting Italian research by providing researchers working in Italy with free access to cutting-edge technologies and expertise.

Job Description

Human Technopole (HT) is a new interdisciplinary life science research institute, created and supported by the Italian government, with the aim of developing innovative strategies to improve human health. HT has the mission of conducting cutting-edge research and to translate innovation into methods and tools available to the entire National scientific community. To this end, HT is opening National Facilities that will provide world-class research infrastructure in the areas of Structural Biology, Light Imaging Microscopy, Genomics, Genome Engineering, and Data Handling and Analysis, aimed at boosting Italian research by providing researchers working in Italy with free access to cutting-edge technologies and expertise.

The National Facility for Genome Engineering and Disease Modeling (GEDI) is hiring a Technician / Senior Technician in Gene Editing to join the Gene Editing Unit. GEDI advances patient-specific disease modeling by integrating stem cell biology, genome engineering technologies, and the generation of stem cell-derived tissue models. These technologies converge within a state-of-the-art automated laboratory, designed to translate, benchmark, and standardize experimental protocols into robust, reproducible workflows. The facility leverages high-throughput robotics and bioengineering platforms through a highly multidisciplinary framework.

The successful candidate will contribute to the implementation and optimization of genome engineering pipelines, focusing on the generation of genome-edited pluripotent stem cells and other cell lines. Reporting to the Head of Facility and working closely with the Manager of the Gene Editing Unit, the new colleague will play a key role in delivering genome editing services and supporting research in the field.

Key Tasks And Responsibilities

• Establish and standardize gene editing technologies (e.g., CRISPR-Cas-mediated NHEJ, HDR, base and prime editing) in pluripotent stem cells and cell lines.
• Design, execute, and troubleshoot genome engineering experiments in coordination with the Facility team.
• Develop and refine innovative genome engineering strategies.
• Maintain detailed records of edited cell lines and associated inventory.
• Support facility management tasks, including inventory control, equipment monitoring, and reagent / sample tracking.

Job Requirements

Essential requirements :

• Master’s degree in Molecular Biology, Biotechnology, or a related life science discipline.
• At least 3 years of post-degree hands-on experience in molecular biology or genome engineering (research or industry setting).
• Proficiency in CRISPR / Cas genome editing, including design and generation of knock-out models, point mutations, and / or reporter lines.
• Experience in molecular biology techniques (e.g., DNA / RNA handling, cloning, RT-PCR, Western blotting).
• Extensive hands-on experience with mammalian cell culture, including maintenance, transfection, clonal selection, and expansion.
• Proficiency in English (spoken and written); HT is an international research environment.

Preferred Requirements

• PhD in Molecular Biology, Biotechnology, or a related discipline.
• Hands-on experience with advanced CRISPR technologies (e.g., base editing, prime editing, CRISPRa / i).
• Familiarity with high-throughput methodologies and / or laboratory automation systems.
• Experience with 3D cell culture models and / or organoid systems.
• Exposure to next-generation sequencing (NGS) or single-cell omics workflows.
• Proven ability to establish and characterize stable cell lines.
• Demonstrated ability to perform routine and technically demanding lab procedures.

Organizational And Social Skills

• Ability to manage multiple priorities in a dynamic environment and work independently.
• Collaborative mindset and ability to work effectively within a multidisciplinary team.

Strong interpersonal skills and a proactive, problem-solving attitude.

• Excellent organizational and communication abilities, including experience in scientific training or presentations
• Cultural sensitivity and respect for diversity in an international, multicultural work environment.

Application Instructions

Please Apply By Sending

i) a CV

ii) a motivation letter in English, specifying where the candidate’s skills meet the requirements listed above

iii) names and contacts of at least 2 referees

Questions concerning the role and any queries regarding the terms and conditions should be sent to (terms and conditions) (these email address should not be used to send applications).

Why Human Technopole

HT seeksscientific excellence, we recruit the best scientific talents through international, open calls.

Our working environment isinternational,friendlyandinclusive. Our scientistswork together across disciplineson research topics of biomedical relevance,leveraging synergiesbetween their diverse skillsets and methodological approaches.

We believe thathighly diverse teams yield the best and most innovative results.

We engage inoutward-facing scientific activitiesaimed at benefiting the national and internationalresearch community.Training is also at the heart of our activity, with initiatives and opportunities for our staff, including scientific courses, conferences and workshops.

• Work-life balance provisions
• Italian language training for foreigners
• Maternity leave up to 1 year and other support for new parents
• Possibility of flexible working hours
• Support for relocation
• Tax benefits where applicable.

Number of positions offered : 1

Contract offered : Fixed-term (3 years) with possibility of renewal - CCNL Chimico Farmaceutico - Employee level

Salary range : 35k-41k, based on candidate’s seniority.

The position is based in Milan .

The Foundation reserves the right, at its sole discretion, to extend, suspend, modify, revoke, or cancel this job posting without giving rise to any rights or claims whatsoever in favour of the candidates; the Foundation reserves, however, the right not to proceed with the awarding of the above-described assignment due to the effect of supervening regulatory provisions and / or obstructive circumstances.

Seniority level

Seniority level

Mid-Senior level

Employment type

Employment type

Contract

Job function

Job function

Engineering and Information Technology

Research Services

Referrals increase your chances of interviewing at Human Technopole by 2x

Get notified about new Senior Technician jobs in Milan, Lombardy, Italy .

Cinisello Balsamo, Lombardy, Italy 16 hours ago

TECNICO REAL ESTATE ADVISORY, TRANSACTION & PROPERTY MANAGEMENT

Pieve Emanuele, Lombardy, Italy 2 weeks ago

Busto Garolfo, Lombardy, Italy 4 weeks ago

MANUTENTORE IMPIANTI TERMICI E FRIGORIFERI

Manutentore - NH Collection Milano City Life - Minor Hotels - Southern Europe

We’re unlocking community knowledge in a new way. Experts add insights directly into each article, started with the help of AI.

J-18808-Ljbffr