Technician in Multi-omics Technologies – National Facility for Genomics

Human Technopole Foundation; Milano; In loco; EUR 35.000; Tempo pieno

Descrizione del lavoro

Join a forward-thinking foundation as a Technician in Multi-omics Technologies. This role involves cutting-edge research in genomics, focusing on single-cell and spatial analysis. Collaborate with a dynamic team, utilizing state-of-the-art technologies to push the boundaries of multi-omics research. You'll be responsible for sample preparation, managing sequencing platforms, and developing innovative protocols. This is an exciting opportunity to contribute to impactful scientific advancements in a vibrant, inclusive environment that values diversity and innovation. If you're passionate about life sciences and eager to make a difference, this position is for you.

Servizi

Welfare plans

Canteen service

Work-life balance provisions

Italian language training

Maternity leave up to 1 year

Flexible working hours

Remote working policy

Support for relocation

Competenze

• Hands-on experience with single-cell and spatial-omics technologies.
• Knowledge of NGS sequencing and molecular biology techniques.
• Fluency in English required for international collaboration.

Mansioni

• Perform sample and library preparation for transcriptomics protocols.
• Operate and manage software for data collection and analysis.
• Assist in developing SOPs and experimental pipelines.

Conoscenze

Single-cell omics technologies

Spatial transcriptomics

NGS sequencing platforms

Molecular biology techniques

Laboratory protocols

Bioinformatics tools

Formazione

Master’s degree in biology

Master’s degree in genetics

Master’s degree in biochemistry

Strumenti

Illumina sequencers

MGI sequencers

Oxford Nanopore sequencers

10x Genomics library preparation

Nanostring protocols

Descrizione del lavoro

APPLICATION CLOSING DATE: June 10th, 2025

The Human Technopole Foundation is looking for a Technician in Multi-omics Technologies for the IU2 Multi-Omics Technologies unit of the National Facility for Genomics.

The National Facility for Genomics provides state-of-the-art and innovative services in genomics. Its core mission is to implement robust experimental and analytical workflows to probe all major domains of genomic exploration, including but not limited to the analysis of DNA, RNA, chromatin and other markers of epigenetic and regulatory activity. These techniques can be applied to diverse areas of biology, with resolution spanning to whole organisms, to tissues or individual cells. Overall, NF Genomics aims to empower research in all domains of genomics for the Italian scientific community at large.

The NF for Genomics foresees four Infrastructural Units (IU):

UI1 High Throughput Sequencing mainly focused on providing state-of-the-art high-throughput sequencing services. This dedicated unit specializes in delivering top-tier genomics, transcriptomics, and epigenomics analyses, employing the latest protocols for sample processing and sequencing.

UI2 Multi-Omics Technologies specialized in multi-omics technologies. Its focus extends to providing cutting-edge services in single-cell and spatial multi-omics analysis, as well as long-read sequencing. This Unit closely collaborates with the Tissue Processing Unit and NF-Imaging, specifically dedicated to implementing spatial transcriptomics protocols.

UI3 Technology Development stays at the forefront of innovation, this dedicated team is committed to methods and technology development. The highly qualified staff is continuously engaged in the evaluation of new technologies and instruments, considering them for acquisition into our facility. We specialize in the optimization and scale-up of custom experimental protocols, offering these services to the broader scientific community.

UI4 Computational Genomics is the computational core of the NF Genomics, the team is dedicated to developing, implementing, and maintaining automated pipelines for the pre-processing and primary data analysis of sequencing data. This unit closely collaborates with the NF for Data Handling and Analysis.

In the context above outlined, the Technician in Multi-omics Technologies, reporting directly to the Senior Manager of the IU2, will become part of the team of the Multi-Omics Technologies unit of the National Facility for Genomics. At Infrastructural Unit 2, we work at the forefront of innovation in multi-omics research. We employ state-of-the-art technologies and protocols for multi-omics analysis, continually pushing boundaries by implementing and applying innovative methods. Our commitment to staying ahead in this dynamic field ensures that our external and internal users benefit from the latest advancements and methodologies. Infrastructural Unit 2 works in tandem with IU 4 and the NF for Data Handling and Analysis. This strong interaction is pivotal in setting up and developing new methods and bioinformatic analysis pipelines.

Key tasks and responsibilities

• Perform sample and library preparation for various single-cell and spatial transcriptomics protocols, including automation-intensive workflows.

• Operate and manage proprietary software for single-cell and spatial transcriptomics platforms and software supporting data collection

• Use of NGS sequencers (i.e. Illumina, MGI, Oxford Nanopore platforms)

• Assist in developing and implementing standard operating procedures (SOPs) and experimental pipelines.

• Contribute to general facility management, including inventory control of samples, reagents, and equipment providing regular updates to colleagues and line manager

Mandatory requirements:

• Master’s degree in biology, genetics, biochemistry, or a related life sciences field.

• At least 1 year of hands-on experience with single-cell and/or spatial-omics technologies, including library preparation with 10x Genomics and/or Nanostring protocols.

• Knowledge of NGS sequencing platforms (i.e. Illumina, MGI )

• Practical experience with molecular biology techniques and laboratory protocols (e.g. digital electrophoresis, qPCR, quality controls checks).

• Background in histology and imaging techniques.

• Fluency in English (HT is an international research institute).

Preferred requirements:

• Experience with single-molecule sequencing technologies (e.g., Nanopore)

• Knowledge of bioinformatic tools for handling, storing, and preparing genomic data files.

• Previous experience in a core facility.

Organizational and social skills:

• Excellent attention to detail, strong organizational skills, and a proactive problem-solving mindset.

• Strong communication, teamwork, and problem-solving skills.

• Ability to independently develop, optimize, and implement research support within a collaborative team environment.

• Ability to interact effectively with colleagues, other teams’ members and work synergistically to drive projects forward.

Application Instructions

Please apply online by sending

I) a CV

II) a motivation letter in English

III) names and contacts of 2 referees

Questions concerning the role and any queries regarding the terms and conditions should be sent to [e-mail] (terms and conditions) (these email address should not be used to send applications).

Why Human Technopole

• HT seeks scientific excellence, we recruit the best scientific talents through international, open calls;

• Our working environment is international, friendly and inclusive. Our scientists work together across disciplines on research topics of biomedical relevance, leveraging synergies between their diverse skillsets and methodological approaches;

• We believe that highly diverse teams yield the best and most innovative results;

• We engage in outward-facing scientific activities aimed at benefiting the national and international research community. Training is also at the heart of our activity, with initiatives and opportunities for our staff, including scientific courses, conferences and workshops.

Main benefits

• Welfare plans.

• Canteen service.

• Work-life balance provisions.

• Italian language training for foreigners.

• Maternity leave up to 1 year and other support for new parents.

• Flexible working hours.

• Remote working policy.

• Support for relocation.

Special consideration will be given to candidates who are part of the protected categories list, according to L. 68/99.

Number of positions offered:1

Contract offered:CCNL Chimico Farmaceutico, Fixed-term 3 years in first instance with option for extension - employee level.

Salary:€ 35k

The position is based inMilan

“The Foundation reserves the right, at its sole discretion, to extend, suspend, modify, revoke, or cancel this job posting without giving rise to any rights or claims whatsoever in favor of the candidates; the Foundation reserves, however, the right not to proceed with the awarding of the above-described assignment due to the effect of supervening regulatory provisions and/or obstructive circumstances”.