Study of the cellular and molecular mechanisms of inflammation and oxidative stress in cardiovascular pathophysiology, using experimental models and cell and molecular biology techniques.

Italian Ministry of Education, University and Research; Italia; On-site; EUR 45,000 - 65,000; Full time

Job summary

Sapienza Università di Roma invites applications for a research position focusing on the cellular and molecular mechanisms underlying inflammation and oxidative stress in cardiovascular pathophysiology.

The project emphasizes patients at high cardiovascular risk and aims to combine analysis of biological samples with in vitro models and molecular biology techniques to understand activation, reactive oxygen species, and interactions among platelets and vascular cells.

Qualifications

• Eligibility: maximum total score is 100 points across qualifications, curriculum vitae and publications.
• Eligibility: 60 points for qualifications, CV, and publications; 40 points for the interview.
• Location: Italy.

Responsibilities

• Investigate cellular and molecular mechanisms of inflammation and oxidative stress in cardiovascular pathophysiology.
• Integrate analysis of biological samples with in vitro models and cellular/molecular biology techniques.

Job description

Organisation/Company Sapienza Università di Roma Research Field Medical sciences Researcher Profile Recognised Researcher (R2) Leading Researcher (R4) First Stage Researcher (R1) Established Researcher (R3) Application Deadline 3 Dec 2026 - 23:59 (UTC) Country Italy Type of Contract To be defined Job Status Not Applicable Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No

Offer Description

The project aims to investigate the cellular and molecular mechanisms underlying inflammation and oxidative stress in cardiovascular pathophysiology, with particular emphasis on patients at high cardiovascular risk. By integrating the analysis of biological samples with in vitro experimental models and cellular and molecular biology techniques, the study will explore the mechanisms regulating cellular activation, reactive oxygen species production, and interactions among platelets, immune cells, and vascular cells. Particular attention will be devoted to the assessment of inflammatory and oxidative stress biomarkers, as well as molecular pathways involved in vascular dysfunction and thromboinflammatory processes. These investigations will contribute to a better understanding of the biological mechanisms associated with cardiovascular disease development and progression.

Additional Information

Eligibility criteria

Maximum total score: 100 points, consisting of 60 points for qualifications, curriculum vitae, and publications, and 40 points for the interview.

• Italy

Eligibility of fellows: country/ies of residence:

• OTHER

Eligibility of fellows: nationality/ies: