Senior Technician / Lab Manager Position In Molecular Cardiology

Buscojobs; Emilia-Romagna; In loco; EUR 50.000 - 70.000; Tempo pieno

Descrizione del lavoro

A prestigious research university in Milan is seeking a Technician/Lab Manager for the Group of Cardiac Development. Candidates should have a MSc or PhD in Biology or Biotechnology and strong skills in molecular biology. Responsibilities include managing experiments with transgenic mouse models and iPS cell culture. The position offers good training opportunities in a creative research environment with international collaboration potential.

Servizi

Good training opportunities

Creative research environment

Competenze

• MSc or PhD degree in Biology or Biotechnology required.
• Strong technical skills in molecular and cellular biology are essential.
• Experience in mouse handling and FELASA accreditation recommended.
• Experience in iPS cell culture preferred.
• Good knowledge of verbal and written English is necessary.

Mansioni

• Conduct experiments using transgenic mouse models.
• Perform iPS cells culture and differentiation to cardiomyocytes.
• Conduct histological and functional analysis.
• Perform molecular biology experiments like RNA-seq.
• Support for grant applications and project reports.

Conoscenze

Technical skills in molecular and cellular biology

Mouse handling

iPS cell culture

Organizational skills

Communication skills

Analytical skills

Formazione

MSc or PhD in Biology, Biotechnology, or similar

Strumenti

Molecular biology techniques

Histological analysis

FACS sorting

Descrizione del lavoro

Senior Technician / Lab Manager Position in Molecular Cardiology

Location

University of Milan and IRCCS Monzino Cardiology Center, Milan, Italy

Host Lab

Group of Cardiac Development, Remodeling and Regeneration

1 year with possibility of extension for 5 years

A position for a Technician / Lab Manager is available in the Group of Cardiac Development, Remodeling and Regeneration under the supervision of Dr. Paola Cattaneo. The group is part of the University of Milan a center of Excellence and one of the biggest University in Italy and is located at the Monzino Cardiology Center in Milan, Italy.

The research focus of the Cattaneo group is to decipher mechanisms by which transcription factors, regulatory elements and epigenetic enzymes orchestrate heart development, cardiac regeneration and fibrosis.

The person will help managing and executing projects focusing on understanding transcriptional and epigenetic mechanisms controlling fibroblast activation as well as RNA translational mechanisms controlling cardiomyocyte differentiation and maturation. Specific techniques will include analyses of mouse models, induced pluripotent stem cells and primary cell culture using a variety of molecular, biochemical and functional techniques (such as advanced microscopy and genomics / transcriptomics).

The selected candidate will be in charge of executing techniques critical for several of the lab’s projects. Preference will be given to candidates with experience in mice handling and / or iPSCs culture and differentiation.

Prospective start date : September 2024- December 2024

The contract is initially of 1 year with possibility of extension for 5 years.

Salary scale is to be determined based on previous work experience.

The position is based in Milan, Italy.

General requirements :

• MSc or a PhD degree in Biology, Biotechnology or similar subjects.
• Strong technical skills in molecular and cellular biology.
• Previous experience in mouse handling and FELASA accreditation is highly recommended
• Previous experience in iPS cell culture is considered a preferential requirement.
• Organizational and lab managing skills, time efficient, good communication skills and open mind.
• Independent working method but also team-oriented work.
• Strong analytical skills and a creative, problem solving-oriented mindset are required.
• Good knowledge of verbal and written English

Main Tasks :

Conducting experiments using transgenic mouse models (colony management, treatments and organ harvest).

iPS cells culture and differentiation to cardiomyocytes.

Histological and functional analysis for the characterization of cardiac phenotypes

FACs sorting and primary cell culture

Molecular biology experiments (e.g. cloning, RNA-seq, ChIP-seq and ATAC-seq).

Support for grant applications, project reports and paper preparation.

We offer very good training opportunities, a varied, creative research environment and possibility to join projects in collaboration with international groups (USA and Europe).

Please send your application with your CV, a letter of motivation and two reference letters or contact of previous supervisors to Dr. Paola Cattaneo :

Please use “Tech / Lab Manager Application” as subject of the email.

Our group advocates equal rights for women, men and minorities. We strongly encourage everyone to apply.

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