Sea Urchin Cell-Type Atlas & Lineage Tracing

Italian Ministry of Education, University and Research; Italia; In loco; EUR 28.000 - 36.000; Tempo pieno

Descrizione del lavoro

Stazione Zoologica Anton Dohrn in Italy seeks a Researcher to analyze single-nucleus RNA sequencing datasets to characterize post-metamorphic cell types and investigate their developmental dynamics.

The project includes generating cell type–specific bulk ATAC-seq datasets from pre- and post-metamorphic sea urchin stages. Using HCR-ISH and IHC, the candidate will validate and spatially map cell types, while live imaging and transgenic approaches trace origins and lineage relationships.

Competenze

• MSc degree in Biology or equivalent qualification obtained abroad.
• Knowledge of English.

Mansioni

• Analyze existing single-nucleus RNA sequencing datasets to characterize post-metamorphic cell types.
• Generate cell type–specific bulk ATAC-seq datasets from pre- and post-metamorphic sea urchin stages.
• Validate and spatially map post-metamorphic cell types using HCR-ISH and IHC.
• Use live imaging and transgenic approaches to trace developmental origins and lineage relationships.

Conoscenze

Knowledge of English

Formazione

MSc degree in Biology

Descrizione del lavoro

Stazione Zoologica Anton Dohrn in Italy seeks a Researcher to analyze single-nucleus RNA sequencing datasets to characterize post-metamorphic cell types and investigate their developmental dynamics.

The project includes generating cell type–specific bulk ATAC-seq datasets from pre- and post-metamorphic sea urchin stages. Using HCR-ISH and IHC, the candidate will validate and spatially map cell types, while live imaging and transgenic approaches trace origins and lineage relationships.