Research assistant in Functional Genomics

Fondazione Links; Candiolo; In loco; EUR 30.000 - 40.000; Tempo pieno

Descrizione del lavoro

A prestigious research institute in Candiolo is seeking motivated candidates for positions in functional genomics research related to gastrointestinal cancer. The role involves conducting CRISPR-based screenings and optimizing genomic protocols. Candidates should have a Bachelor's degree in a relevant field and at least one year of experience with techniques like molecular cloning and flow cytometry. Competitive remuneration and a renewable contract up to 24 months are offered.

Competenze

• 1 year experience in at least one listed subject.
• Good command of the English language.
• Knowledge of Italian is an advantage.

Mansioni

• Conduct CRISPR-based functional screening using patient-derived cancer tumoroids.
• Optimize protocols and strategies for FACS-based functional genomics screening.
• Contribute to ongoing research group activities.

Conoscenze

Molecular cloning

Pooled genetic screening

Flow cytometry

Mammalian tissue culture

Critical thinking

Effective communication in cross-cultural environments

Adaptability

Formazione

Bachelor’s degree in biotechnology, biology, medicine, chemical biology, pharmacy or a related field

Descrizione del lavoro

Overview

IIGM is located at the FPO IRCCS Candiolo Cancer Institute, Candiolo, Turin - Italy. The main goal of IIGM and FPO IRCCS Candiolo is to foster and develop excellence in research and education, with special reference to cancer biology and cancer biomarker discovery. The institute provides high-level scientific education for students and post-doctoral fellows, and access to state-of-the-art research facilities and international networks.

Gender Equality Plan: diversity is our legacy and our future. Be part of it. At IIGM diversity is an integral part of our culture and identity and for this we have adopted a plan for gender equality (GEP). We promote diversity and inclusion because we recognize that they are a source of strength and competitive advantage.

The Chemical Biology Lab at the Italian Institute for Genomic Medicine (IIGM) is seeking highly motivated candidates at all levels of seniority (predoc, postdoc) to work in functional genomics and epigenetics within the context of gastrointestinal cancer research. The laboratory investigates key aspects of drug tolerance and its involvement in tumor recurrence, with a focus on a subset of cancer cells that can survive therapy by entering a reversible, slow-proliferative state that is challenging to target with standard treatments. The project aims to identify the underlying biological mechanisms and apply research findings to develop potential therapeutic strategies. The Institute provides state-of-the-art Genomics and single-cell Genomics Sequencing platforms.

Responsibilities

• conduct CRISPR-based functional screening using patient-derived cancer tumoroids;
• optimize protocols and strategies for FACS-based functional genomics screening;
• contribute to ongoing research group activities and collaborative projects

Qualifications and requirements

• Bachelor’s degree in biotechnology, biology, medicine, chemical biology, pharmacy or a related field
• 1 year experience in at least one of the following subjects:
  • molecular cloning
  • pooled genetic screening
  • flow cytometry
  • mammalian tissue culture (cells and/or organoids)
• good command of the English language
• knowledge of Italian is an advantage, but not strictly necessary
• curiosity and active learning
• critical thinking and problem-solving
• time management
• adaptability and flexibility
• effective communication in cross-cultural environments

Interested candidates should include

• research proposal (for postdoc applicants only)
• certificates, transcripts including all grades of your previous qualifications, and a list of publications

Positions: no. 02

Offered contract: Coordinated and Continuous Collaboration contract (Co.Co.Co.) on a project basis duration to be defined, renewable up to 24 months. Competitive remuneration based on the candidate’s personal qualifications.